Results 91 to 100 of about 750,741 (278)

Driver-pressure-impact and response-recovery chains in European rivers: observed and predicted effects on BQEs [PDF]

open access: yes, 2011
The report presented in the following is part of the outcome of WISER’s river Workpackage WP5.1 and as such part of the module on aquatic ecosystem management and restoration. The ultimate goal of WP5.1 is to provide guidance on best practice restoration
Dahm, V.   +7 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

DESFOLHAÇÃO DE PERFILHOS EM PASTO DE CAPIM-BRAQUIÁRIA SOB LOTAÇÃO CONTÍNUA

open access: yesCiência Animal Brasileira, 2011
The objective of this study was to evaluate the number oftillers with different levels of defoliation and theircharacteristics on the Brachiaria decumbens cv. Basilisk pasture.
MANOEL EDUARDO ROZALINO SANTOS   +4 more
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Estrutura do capim-braquiária durante o diferimento da pastagem = Signalgrass structure during pasture deferment

open access: yesActa Scientiarum: Animal Sciences, 2010
O experimento foi realizado para avaliar o número de perfilhos, a massa de forragem e de seus componentes morfológicos em pastos de Brachiaria decumbens cv. Basilisk durante o diferimento da pastagem.
Manoel Eduardo Rozalino Santos   +4 more
doaj  

A Learning Framework for Morphological Operators using Counter-Harmonic Mean

open access: yes, 2012
We present a novel framework for learning morphological operators using counter-harmonic mean. It combines concepts from morphology and convolutional neural networks.
D. Scherer   +8 more
core   +3 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Geochemical analysis of Cenozoic fossil conifers at high latitudes: Implications for molecular preservation and environmental change [PDF]

open access: yes, 2010
Fossil materials record ancient life and their adapted environment. Arctic plant fossils are critical for our understanding of the Earth’s paleoenvironment when high latitudes were under ice-free conditions.
Witkowski, Caitlyn
core   +1 more source

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