Results 151 to 160 of about 3,461,047 (301)

Hydrodynamics and Morphology on Composite Beaches

open access: yes
Abstract Composite beaches, characterised by a dissipative sand beach backed by a steep cobble berm, exhibit unique hydro and morphodynamic behaviors due to their bimodal sediment size distribution. This study analyzes morphological variability and wave runup on a composite beach in Borth, Wales, using continuous Lidar data collected ...
Chris Blenkinsopp   +3 more
openaire   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Certificate of affiliation given to Slate, Tile and Composition Roofers, Damp and Waterproof Workers by United Slate, Tile and Composition Roofers, Damp and Waterproof Workers' Association

open access: yes, 1937
Certificate of affiliation given to Slate, Tile and Composition Roofers, Damp and Waterproof Workers by United Slate Tile and Composition Roofers, Damp and Waterproof Workers' Association, local union #62, Springfield, Missouri.
United Slate, Tile and Composition Roofers, Damp and Waterproof Workers' Association
core  

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

Morphology and body composition

open access: yesThe Journal of Physical Fitness and Sports Medicine, 2020
openaire   +2 more sources

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

open access: yesFEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt   +2 more
wiley   +1 more source

BIODIVERSITY IN MORPHOLOGICAL AND PHYSICO-CHEMICAL CHARACTERISTICS OF WILD RASPBERRY (Rubus idaeus L.) GERMPLASM COLLECTED FROM TEMPERATE REGION OF AZAD JAMMU & KASHMIR (PAKISTAN)

open access: yesActa Scientiarum Polonorum: Hortorum Cultus, 2014
Wild raspberry (Rubus idaeus L.) is abundantly grown and widely distributed in temperate regions of lower Himalayan range which represents rich biological diversity for raspberry.
Maqsood Ahmed   +3 more
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Home - About - Disclaimer - Privacy