Results 81 to 90 of about 25,419,403 (282)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Spatial Point Pattern Analysis and Industry Concentration [PDF]

open access: yes
Traditional measures of spatial industry concentration are restricted to given areal units. They do not make allowance for the fact that concentration may be differently pronounced at various geographical levels. Methods of spatial point pattern analysis
Hans-Friedrich Eckey   +2 more
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Process of Incorporation and Morphological Transformations of Rural Settlement Patterns in the Context of Urban Development. The Case Study of Łódź

open access: yesQuaestiones Geographicae, 2020
The subject of the research covers the problem of morphological changes in former villages incorporated into the city on the example of Łódź. The first objective of the article is to analyse the urban development of the city, taking into account the ...
Figlus Tomasz
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Quantifying and Mapping the Impact of Construction Land Expansion on Cultivated Land Fragmentation—A Case Study of Fuqing City, China

open access: yesAgriculture
To ensure the sustainable utilization of cultivated land resources, it is essential to quantify and map the characteristics of construction land and cultivated land and analyze the mechanisms by which construction land expansion affects cultivated land ...
Xiaoran Yang, Xiping Zheng, Xinyang Yu
doaj   +1 more source

Spatial Analysis of a mixed Beech, Spruce and Fir stand in the Eastern Alps [PDF]

open access: yes, 2010
In a forest reserve, located in the Eastern Italian Alps, a 4 ha permanent plot has been set up in a beech-spruce-fir multilayered forest, left to natural evolution for more than 30 years, in order to detect stand structure and spatial patterns ...
Marin, Alberto
core  

Small-scale spatial pattern and dynamics of experimental plant communities [PDF]

open access: yes, 2007
Plant-plant interference is inherently local and seed dispersal generally limited. Both processes generate spatial and genetic structure within plant populations and communities that need to be better understood in order to predict dynamic community ...
Monzeglio, Ursula
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

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