Results 81 to 90 of about 349,685 (286)

Driver-pressure-impact and response-recovery chains in European rivers: observed and predicted effects on BQEs [PDF]

, 2011
The report presented in the following is part of the outcome of WISER’s river Workpackage WP5.1 and as such part of the module on aquatic ecosystem management and restoration. The ultimate goal of WP5.1 is to provide guidance on best practice restoration
Dahm, V., Feld, C.K., Keizer-Vlek, H.E., Logez, M., Lorenz, A., Marzin, A., Michels, H.C.U., Verdonschot, P.F.M.   +7 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Construction and optimization of Green Infrastructure Network in mountainous cities: a case study of Fuzhou, China

Scientific Reports
Green infrastructure networks enhance the protection and improvement of urban ecological environments, augment the efficiency and quality of ecosystem services, and furnish residents with healthier and more comfortable living conditions.
He Huang, Danling Fu, Guochang Ding, Chen Yan, Xiangcai Xie, Yaling Gao, Qunyue Liu   +6 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

On morphological hierarchical representations for image processing and spatial data clustering

, 2012
Hierarchical data representations in the context of classi cation and data clustering were put forward during the fties. Recently, hierarchical image representations have gained renewed interest for segmentation purposes. In this paper, we briefly survey
A. Baraldi, A. Rosenfeld, C. Jardine, C. Mattiussi, C. Ronse, C. Zahn, D. Wishart, E. Breen, F. Dias, F. Meyer, F. Meyer, F. Meyer, G. Bertrand, G. Estabrook, G. Matheron, G. Ouzounis, J. Cousty, J. Cousty, J. Cousty, J. Cousty, J. Cousty, J. Gower, J. Kruskal, J. Serra, J. Shi, J.P. Barthélemy, J.P. Benzécri, K. Florek, K. Spärck Jones, L. Gueguen, L. Guigues, L. Guigues, L. Hubert, L. Hubert, L. Hubert, L. Najman, L. Najman, L. Najman, L. Najman, L. Vincent, M. Nagao, M. Nagao, N. Ahuja, N. Jardine, N. Jardine, N. Jardine, O. Morris, P. Arbeláez, P. Felzenszwalb, P. Nacken, P. Salembier, P. Salembier, P. Salembier, P. Sneath, P. Soille, P. Soille, P. Soille, P. Soille, P. Soille, P. Soille, P. Soille, R. Adams, R. Cormack, R. Graham, R. Jones, R. Levillain, R. Marfil, R. Sokal, S. Beucher, S. Horowitz, S. Johnson, S. Zucker, T. Kong, T. Sørensen, W.G. Kropatsch, Z. Wu   +75 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Process of Incorporation and Morphological Transformations of Rural Settlement Patterns in the Context of Urban Development. The Case Study of Łódź

Quaestiones Geographicae, 2020
The subject of the research covers the problem of morphological changes in former villages incorporated into the city on the example of Łódź. The first objective of the article is to analyse the urban development of the city, taking into account the ...
Figlus Tomasz
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Quantifying and Mapping the Impact of Construction Land Expansion on Cultivated Land Fragmentation—A Case Study of Fuqing City, China

Agriculture
To ensure the sustainable utilization of cultivated land resources, it is essential to quantify and map the characteristics of construction land and cultivated land and analyze the mechanisms by which construction land expansion affects cultivated land ...
Xiaoran Yang, Xiping Zheng, Xinyang Yu
doaj   +1 more source