Results 91 to 100 of about 537,113 (312)

Morphological variability of Navicula perminuta Grunow

open access: yesJapanese Journal of Water Treatment Biology, 1992
Approximately 500 specimens of Navicula perminuta Grunow. were analyzed from light micrographs on the basis of the shape of valve, apices, the direction and density of the striae at the centre, the shape and width of the central area, and the length and breadth of the valve. The data were compared withprevious description of Navicula perminuta Grunow.
Hiroshi Fukushima   +3 more
openaire   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Morphological variability of Cymbella japonica Reichelt

open access: yesJapanese Journal of Water Treatment Biology, 1992
397 individuals were researched on material from Tane Pond, Tottori City. The various structures of frustule and their frequencies are shown in Table 1.These frequency show no great difference from those published before for frequency calculations based on microphotograph. Frustule lengths range from 43.5-58μm, width 10.5-14μm, with striae density from
Hiroshi Fukushima   +3 more
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

The variability of natural populations of Brachypodium pinnatum and B. sylvaticum based on morphological features

open access: yesActa Societatis Botanicorum Poloniae, 2011
The morphological diversity in 25 populations of two native species of Brachypodium occurring in Poland, was studied. Principal component analysis and cluster analysis of morphometric data segregate specimens or populations of Brachypodium into two ...
Beata Paszko
doaj   +1 more source

The morphological variability of the piriformis muscle

open access: yesFolia Morphologica
The aim of the study is to create several classifications of the piriformis muscle (PM): proximal and distal attachments, potential fusions, and the relationship with the sciatic nerve. It is the first comprehensive anatomical examination of this subject.One hundred and twenty-four lower limbs from 62 cadavers, fixed in 10% formalin, were examined.The ...
Łukasz, Olewnik   +8 more
openaire   +2 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

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