Results 51 to 60 of about 359,534 (195)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

AFLP molecular characterizations of some Saccobolus species (Ascomycota, Pezizales) [PDF]

, 2011
Amplified restriction fragment length polymorphisms (AFLP) were used to assess the genetic diversity among species and isolates of the genus Saccobolus. Monosporic strains of five Saccobolus species were used throughout.
Cinto, Isabel Esther, Ramos, Araceli Marcela, Ranalli, Maria Esther, Tadic, Luis Franco   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Modeling the effect of soil meso- and macropores topology on the biodegradation of a soluble carbon substrate [PDF]

, 2015
Soil structure and interactions between biotic and abiotic processes are increasingly recognized as important for explaining the large uncertainties in the outputs of macroscopic SOM decomposition models.
Chenu, Claire, Coquet, Yves, Falconer, Ruth E., Garnier, Patricia, Makowski, David, Nunan, Naoise, Pot, Valérie, Raynaud, Xavier, Vieublé-Gonod, Laure, Vogel, Laure E.   +9 more
core   +5 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Morphological variability of Navicula perminuta Grunow

Japanese Journal of Water Treatment Biology, 1992
Approximately 500 specimens of Navicula perminuta Grunow. were analyzed from light micrographs on the basis of the shape of valve, apices, the direction and density of the striae at the centre, the shape and width of the central area, and the length and breadth of the valve. The data were compared withprevious description of Navicula perminuta Grunow.
Hiroshi Fukushima, Tsuyako Ko-Bayashi, Harue Fujita, Sakiko Yoshitake   +3 more
openaire   +2 more sources

Keragaman Jeruk Fungsional Indonesia Berdasarkan Karakter Morfologis Dan Marka RAPD [PDF]

, 2016
Identification of citrus genetic variability is prerequisite for effective genetic resources management and selection process in breeding program. The objective of the research was to study fifteen accessions of Indonesian functional citrus based on ...
Agisimanto, D. (Dita), Palupi, N. E. (Norry), Yulianti, F. (Farida)   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Morphological variability of Cymbella japonica Reichelt

Japanese Journal of Water Treatment Biology, 1992
397 individuals were researched on material from Tane Pond, Tottori City. The various structures of frustule and their frequencies are shown in Table 1.These frequency show no great difference from those published before for frequency calculations based on microphotograph. Frustule lengths range from 43.5-58μm, width 10.5-14μm, with striae density from
Hiroshi Fukushima, Tsuyako Kobayashi, Yasuto Suzuki, Harue Fujita   +3 more
openaire   +2 more sources

Genetic analysis and qtl mapping of agro-morphological traits in lowland rice (Oryza sativa L.) under drought conditions [PDF]

, 2016
The present study was undertaken to evaluate lowland rice genetic variability associated with agro-morphological traits under drought condition. A set of 250 recombinant inbred lines (RILs) from the cross between rice parental cultivarIR64 (sensitive to ...
Audebert, Alain, Hema, Drissa, Kam, Honore, Konate, Abdourasmane K., Sangaré, Jean Rodrigue, Sanni, Ambaliou, Zongo, Adama   +6 more
core