Results 181 to 190 of about 242,957 (260)

A Cooperative Release of Mitochondrial DNA From Platelets and Neutrophils Drives an Interferon Signature in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

Morphometric Analysis of the Mandibular Condyle and Ramus on Panoramic Radiographs: A Cross-Sectional Study in Hail, Saudi Arabia. [PDF]

Cureus
Alanazi Y, Almagdawi EA, Alanazi RB, Alharbi FY, Alduayyi AK, Altheban AS.   +5 more
europepmc   +1 more source

The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD.
Shayal Vashisth, Aleya Shedd, Ariel Aiken, Solmi Cheon, Josh Bandopadhay, Kiran Kaur, Kimberly M. Huber, Maria H. Chahrour   +7 more
wiley   +1 more source

Secular Changes in Cranial Morphology and Pattern of Sexual Dimorphism in Modern Japanese: A Geometric Morphometric Analysis Using Post-Mortem Computed Tomography Data. [PDF]

Am J Biol Anthropol
Usui S, Amano H, Hayakawa H, Shiotani S, Ogihara N.   +4 more
europepmc   +1 more source

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source

Surgical Management of Isolated Zygomaticomaxillary Complex Fractures: Role of Objective Morphometric Analysis in Decision-Making. [PDF]

Craniomaxillofac Trauma Reconstr
Mijatov S, Mijatov I, Brajković D, Rodić D, Golubović J.   +4 more
europepmc   +1 more source

Shaping research in marine functional connectivity for integrated and effective marine science and management

Biological Reviews, EarlyView.
ABSTRACT Effective knowledge of ecological connectivity at sea and at the land–sea interface is key to supporting global policy goals to conserve and restore ocean biodiversity and function. However, a persistent lack of commonality in terminology and understanding around the concept of connectivity in marine ecological studies hampers its integration ...
Audrey M. Darnaude, Susanne E. Tanner, Andreu Blanco, Anna M. Sturrock, Yael Teff Seker, Angel Pérez‐Ruzafa, Jonne Kotta, Tamar Guy‐Haim, Francisco R. Barboza, Manuel Hidalgo, Katell Guizien, Jerneja Penca, Lucía López‐López, Maria Beger, Federica Costantini, Sophie Arnaud‐Haond, Cynthia Riginos, Kris Hostens, Gil Rilov, Stelios Katsanevakis, Ewan Hunter   +20 more
wiley   +1 more source

Morphological and Morphometric Analysis of the Maxillary Nerve in South Indian Cadavers.

J Pharm Bioallied Sci
Bhat ALS, Rao KGM, Marpalli S.
europepmc   +1 more source

Lingual Concavities in Posterior Mandible: Retrospective Morphometric Analysis in Relation to Gender and Tooth Loss. [PDF]

Int J Dent
Al-Taezi KA, Chen W, Liu L, Cai Z, Muhaisen BOM, Tang C.   +5 more
europepmc   +1 more source

Diet of bird‐like troodontid dinosaurs: synthesis of a contentious clade

Biological Reviews, EarlyView.
ABSTRACT Troodontidae is a clade of small‐to medium‐sized maniraptoran theropods that mainly lived in Laurasia (modern Asia, North America and Europe) during the Jurassic and Cretaceous periods and are believed to have had a variety of diets. The uniqueness of troodontid teeth suggests that they diverged from the typical flesh‐based diet of non‐avian ...
Yui Chi Fan, Case Vincent Miller, Michael Pittman   +2 more
wiley   +1 more source