Results 61 to 70 of about 53,870 (244)

Anti‐Apoptotic and Neurite‐Protective Nanomedicine Augments Embryonic Stem Cells‐Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery

Advanced Science, EarlyView.
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen, Xiaoyan Jiang, Yuanhui Wang, Zhaobin Luo, Yu Zhang, Siwei Liu, Rui Huang, Dandan Zhang, Zhimin Tang, Yahan Ju, Shaohui Pan, Ni Ni, Wei Feng, Yu Chen, Ping Gu   +14 more
wiley   +1 more source

Quantitative Morphometric Characteristics in the Geomorphic Setting of Southern Malang, Indonesia [PDF]

E3S Web of Conferences
Geomorphometry serves as a vital tool for providing quantitative data on watershed characteristics. Morphometric analysis is essential for understanding the relationship between landform features and hydrological responses. This research aimed to examine
Masruroh Heni, Sahrina Alfi, Anam Choirul, Rahmi Zukhrufia, Fatimah Azzahra Zafira, Utomo Kresno Sastro Bangun, Harfian Bintang   +6 more
doaj   +1 more source

Conservation issues and infraspecific polymorphism of Cypripedium guttatum on selected locations in Russia

Nature Conservation Research: Заповедная наука, 2020
The problem of protection and conservation of rare and endangered plant species in the wild is currently the topic of discussion and research worldwide. The Orchidaceae plants are of special concern.
Alexander I. Shirokov, Vera V. Syrova, Alexey V. Salokhin, Ivan N. Markelov, Elena V. Andronova, Elena V. Ganyushkina   +5 more
doaj   +1 more source

Modeling of morphometric parameters of gypsum sinkholes

نشریه جغرافیا و برنامه‌ریزی, 2020
Introduction Maroon plain, located in Maroon basin is situated in Khuzestan, and Kohgiluyeh and Boyer-Ahmad provinces; and Jaber plain is positioned in northwest Ilam City in Ilam Province. The existence of Gachsaran Formation and gypsum karstic phenomena (the most important of which are sinkholes) in the mentioned plains, can have a very devastating ...
Hamide Gholam Heidari, Mozhghan Entezari, Haji Karimi, Mohammadhosein Ramasht   +3 more
openaire   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Acer negundo, morphometric parameters, the level of variability

Naukovì dopovìdì Nacìonalʹnogo unìversitetu bìoresursiv ì prirodokoristuvannâ Ukraïni, 2021
The article investigates the morphometric characteristics of the fruits of Acer negundo L. in the conditions of urbanized ecotops of the Mykolaiv region. Acer negundo an ornamental plant from South America, which was completely naturalized in the conditions of Ukraine. As the data of the literature indicate, A.
openaire   +2 more sources

Developmentally Inspired, Mechanical–Metabolic Dual Gradient Osteochondral Constructs Bridging Regeneration and Therapeutic Screening

Advanced Science, EarlyView.
A developmentally inspired osteochondral construct integrates mechanical and metabolic dual gradients within a 3D‐printed platform. Human MSC spheroids are spatially directed to form cartilage–bone interfaces, enabling evaluation of regeneration without biochemical reagents and assessment of drug responses. This physiologically relevant, phase‐specific
Yurim Choi, Wonjun Jang, Raehui Kang, Ulziituya Batjargal, Jihyeon Song, Soojin Park, MinSeok Kim, Hyobum Cho, Junhyung Kim, Yu Shrike Zhang, Han‐Jun Kim, Junmin Lee   +11 more
wiley   +1 more source

Relationship of Humerus Retroversion Angle with Morphometric Parameters

, 2022
Background: This study aims to perform an analysis of the morphometric anatomical measurements of the humerus to make clinically successful evaluations. Material and Method: A total of 42 dry bone humerus were included in the study. Measurement parameters: Length of the humerus (LH), circumference of the surgical neck (CSN), width of the ...
Şenol, Gamze Taşkın, İbrahim Kürtül, Ray, Abdullah, Ahmetoğlu, Gülçin   +3 more
openaire   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source