Results 121 to 130 of about 59,390 (259)

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Proximal femoral morphometry and its association with hip fracture patterns: a systematic review with meta-analysis. [PDF]

Surg Radiol Anat
Kotzias D, Giovanoulis V, Koutserimpas C, Triantafyllou G, Veizi E, Arkoudis NA, Tsakotos G, Troupis T, Piagkou M.   +8 more
europepmc   +1 more source

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source

Agreement and Comparative Performance of Cognitive Testing, Visual MRI Rating, and Automated Brain Morphometry in Older Adults with Suspected Dementia in Uganda. [PDF]

Degener Neurol Neuromuscul Dis
Nassanga R, Kaddumukasa M, Jones SE, Sajatovic M, Nemani A, Basiimwa RC, Kawooya MG, Tumwine JK, Lwere K, Gumikiriza-Onoria JL, Mubuuke AG, Nakasujja N.   +11 more
europepmc   +1 more source

Geometric Morphometrics Reveal Body Shape Variation in Freshwater Shrimps of the Genus Macrobrachium Lacking a Mandibular Palp (Formerly Pseudopalaemon Sollaud, 1911) (Decapoda: Palaemonidae)

Acta Zoologica, EarlyView.
ABSTRACT Shape variation in the cephalothorax of Macrobrachium species without mandibular palp using geometric morphometrics was used as a tool to support species differentiation and propose new diagnostic characters for taxonomic identification.
Thaís Arrais Mota, Ana Carla Soares da Silva, Lucas Jhones de Santana Neves, Carlos Eduardo Rocha Duarte Alencar, Fabrício Lopes Carvalho   +4 more
wiley   +1 more source

Evaluation of Sex-Related Morphometry of the Sella Turcica in Autopsy Using Machine Learning. [PDF]

Diagnostics (Basel)
Depreli A, Ozturk MF, Nasip OF, Yılmaz H, Bakan HU, Sahin NE.   +5 more
europepmc   +1 more source

Altered cytoskeletal integrity underlies impaired platelet shape change and defective thrombus formation in ETV6‐related thrombocytopenia

British Journal of Haematology, EarlyView.
Summary ETV6‐related thrombocytopenia (ETV6‐RT) is an inherited platelet disorder caused by germline ETV6 variants. Despite recent progress, the mechanisms underlying platelet dysfunction in ETV6‐RT remain unclear. We investigated 12 patients from six families using functional assays, electron microscopy, quantitative proteomics and cytoskeletal ...
Ivan P. Tesakov, Julia‐Jessica D. Korobkin, Daria V. Fedorova, Sofia V. Galkina, Maria M. Golomysova, Sergei I. Obydennyi, Anastasia A. Ignatova, Ekaterina‐Iva A. Adamanskaya, Eugenia V. Yushkova, Anna V. Pavlova, Pavel A. Zharkov, Igor I. Kireev, Galina A. Novichkova, Viktor G. Zgoda, Mikhail A. Panteleev, Anastasia N. Sveshnikova   +15 more
wiley   +1 more source

Supreme nasal conchae in human cadavers: prevalence, morphometry, and a new classification proposal. [PDF]

Surg Radiol Anat
Montello MB, Cardenas SHR, da Silva Negreiros Neto T, de Araújo Suassuna GV, Lira-Bandeira WG, Landfald IC, Olewnik Ł, Cavalcante JC, Abreu BJ.   +8 more
europepmc   +1 more source

Artificial intelligence‐based statistical modeling delineates architectural distortion in focal cortical dysplasia

Brain Pathology, EarlyView.
Histopathological identification of subtle cortical architectural abnormalities in focal cortical dysplasia (FCD) resections remains challenging. We investigated if artificial intelligence (AI)‐based morphometric and spatial analysis of NeuN‐stained cortical sections could detect neuronal architectural disorganization in epilepsy resections, including ...
Andrew Cannon, Roland Tian, Blake Ebner, Robert E. Watson Jr., Brian Burkett, Jamie Van Gompel, Lily C. Wong‐Kisiel, Christopher P. Hartley, Roger K. Moreira, Aditya Raghunathan   +9 more
wiley   +1 more source

Against the grain: Leveraging machine learning to analyze mudbrick structures. [PDF]

PLoS One
Kouki S, Lorenzon M, Cutillas-Victoria B, Lichtenberger A, Schreiber T, Zardaryan M, Hein A, Polymeris G.   +7 more
europepmc   +1 more source