Results 31 to 40 of about 452,856 (299)

PREMATURE MORTALITY IN KAZAKHSTAN

Актуальные проблемы теоретической и клинической медицины
Introduction. Premature mortality is often used as an indicator of health system performance. Health authorities track it to identify gaps, prioritize public health measures, and inform policies.
L. Kosherbayeva, N. Alekenova, A. Tabarov, N. Akhtayeva, R. Kosmuratova, A. Kamalbek   +5 more
doaj   +1 more source

Alcohol-related mortality in deprived UK cities: worrying trends in young women challenge recent national downward trends [PDF]

, 2013
Background: Glasgow, the largest city in Scotland, has high levels of deprivation and a poor-health profile compared with other parts of Europe, which cannot be fully explained by the high levels of deprivation.
Shipton, Deborah, Walsh, David, Whyte, Bruce   +2 more
core   +1 more source

The analysis of premature mortality in selected Central and East European countries

Acta Universitatis Carolinae Geographica
Despite mortality improvements across Europe, premature mortality notably persists in Central and East European countries. This study is aimed to assess premature mortality variations across Central and East European countries from 1970 to 2019 ...
Irina Pahomii
doaj   +1 more source

Ectopy on a single 12‐lead ECG, incident cardiac myopathy, and death in the community [PDF]

, 2017
BackgroundAtrial fibrillation and heart failure are 2 of the most common diseases, yet ready means to identify individuals at risk are lacking. The 12-lead ECG is one of the most accessible tests in medicine.
Alonso, Alvaro, Chen, Lin Y, Dewland, Thomas A, Dukes, Jonathan W, Gottdiener, John S, Heckbert, Susan R, Marcus, Gregory M, Nguyen, Kaylin T, Psaty, Bruce M, Soliman, Elsayed Z, Stein, Phyllis K, Vittinghoff, Eric   +11 more
core   +3 more sources

Premature Mortality from Cardiovascular Disease in the Americas - Will the Goal of a Decline of "25% by 2025" be Met? [PDF]

PLoS ONE, 2015
Cardiovascular diseases (CVD) are the underlying cause 1.6 million deaths per year in the Americas, accounting for 30% of total mortality and 38% of by non-communicable deaths diseases (NCDs). A 25% reduction in premature mortality due four main NCDs was
Pedro Ordunez, Elisa Prieto-Lara, Vilma Pinheiro Gawryszewski, Anselm J M Hennis, Richard S Cooper   +4 more
doaj   +1 more source

Spatial epidemiology of premature mortality in Ontario, Canada

International Journal of Population Data Science, 2018
Introduction Geographic disparities in health indicators, such as premature mortality, may reveal area-level weaknesses in health system performance. Monitoring geographic trends can therefore have powerful implications for system evaluation and planning.
Emmalin Buajitti, Tristan Watson, Todd Norwood, Laura Rosella   +3 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Aboriginal premature mortality within South Australia 1999-2006: a cross-sectional analysis of small area results

BMC Public Health, 2011
Background This paper initially describes premature mortality by Aboriginality in South Australia during 1999 to 2006. It then examines how these outcomes vary across area level socio-economic disadvantage and geographic remoteness.
McDermott Robyn, Woollacott Tony, Jury Heather, Banham David, Baum Fran   +4 more
doaj   +1 more source

Premature Mortality in Canada

University of Toronto Journal of Public Health, 2020
Introduction: Premature mortality (deaths before age 75) is a well-established metric of population health and health system performance. In Canada, underlying differences between provinces/territories present a need for stratified mortality trends. Methods: Using data from the Canadian Vital Statistics Database, a descriptive analysis of sex ...
Catherine Liang, Emmalin Buajitti, Laura Rosella   +2 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source