Results 141 to 150 of about 5,850,604 (355)

Identifying the latent classes of modifiable risk behaviours among diabetic and hypertensive individuals in Northeastern India: a population-based cross-sectional study

BMJ Open, 2022
Holendro Singh Chungkham, Strong P Marbaniang, Hemkhothang Lhungdim   +2 more
doaj   +1 more source

Modified Glasgow prognostic score is a pre-surgical prognostic marker of disease mortality in upper urinary tract urothelial carcinoma [PDF]

, 2020
Shunsuke Tsuzuki, Shoji Kimura, Wataru Fukuokaya, Takafumi Yanagisawa, Kenichi Hata, Jun Miki, Takahiro Kimura, Hirokazu Abe, Shin Egawa   +8 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Impact of adult son migration on the health wellbeing of older parents and shifts in caregiving patterns: a study in India

BMC Geriatrics
Background Population ageing is a growing demographic concern in the twenty-first century, with health declining as individuals age. In India, migration, particularly among single males, disrupts traditional caregiving systems, affecting older parents ...
Manoj Dakua, Hemkhothang Lhungdim
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Machine learning predicting mortality in sarcoidosis patients admitted for acute heart failure

, 2022
Qiying Dai, Akil Adrian Sherif, Chengyue Jin, Yongbin Chen, Peng Cai, Pengyang Li   +5 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Mortality due to trauma in cats attending veterinary practices in central and south‐east England [PDF]

, 2017
Jennifer McDonald, Ian R. Cleasby, Dave C. Brodbelt, David B. Church, Dan G. O’Neill   +4 more
openalex   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Hypertension in India: a gender-based study of prevalence and associated risk factors

BMC Public Health
Background Hypertension, a major non-communicable disease, is responsible for a significant number of global deaths, including approximately 17.9 million yearly.
Raza Mohammad, Dhananjay W. Bansod
doaj   +1 more source