Results 251 to 260 of about 2,190,813 (317)

Toward practical screening of mortality risk: Insights from interpretable machine learning in NHANES. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Lin YT, Lin LY, Chuang KJ.
europepmc   +1 more source

Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences

Advanced Science, EarlyView.
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley   +1 more source

Mortality Risk Following a Household Suicide.

JAMA Netw Open
Alves F, Rodrigues EDS, Toledo L, Pescarini JM, Rodrigues RL, Naslund JA, Barreto ML, Patel V, Machado DB.   +8 more
europepmc   +1 more source

Voting behavior and mortality risk in older adults: Evidence from the Wisconsin Longitudinal Study. [PDF]

J Gerontol B Psychol Sci Soc Sci
Handy F, Konrath S.
europepmc   +1 more source

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

Advanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh, Hosni Cherif, Matthew Mannarino, Juiena Sagir, Magali Millecamps, Jean A. Ouellet, Laura S. Stone, Lisbet Haglund   +7 more
wiley   +1 more source

COVID-19 mortality risk among women with ovarian cancer: a matched case-control study. [PDF]

Braz J Med Biol Res
Peruchi KPI, Bastos VAF, Teixeira LA, Pimentel FF, Candido Dos Reis FJ.   +4 more
europepmc   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Predictive Value of Machine Learning for Poststroke Mortality Risk: Systematic Review and Meta-Analysis. [PDF]

J Med Internet Res
Chen Y, Ou Z, Deng Y, Luo A, Li X, Yang Y, Yang Q, Wu X, Zhou M.   +8 more
europepmc   +1 more source

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

Advanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li, Zhongshao Chen, Qianqian Gao, Yuehan Gao, Ning Yang   +4 more
wiley   +1 more source

Mortality risk and causes of death in exogenous Cushing's syndrome: a systematic review and meta-analysis.

J Clin Endocrinol Metab
Limumpornpetch P, Stewart PM, Pujades-Rodriguez M, Baxter PD, Tiganescu A, Nyaga VN, Morgan AW.   +6 more
europepmc   +1 more source