Results 111 to 120 of about 42,215 (293)

Engineered TIGIT‐Blockade Membrane Vesicles Synergize with Microwave Ablation to Mediate Liver Metastases Eradication

Advanced Science, EarlyView.
Microwave ablation (MWA) represents a highly effective and clinically significant therapeutic modality for the treatment of liver metastases. This study develops engineered cell membrane vesicles to specifically target the transition zone of MWA for liver metastases. This strategy can inhibit VEGF‐mediated immunosuppression, block CD155/TIGIT signaling
Shaoyue Li, Weichen Xu, Yuting Shen, Xuexia Shan, Jiawei Sun, Shisi Ding, Xiaodong Hou, Shaoning Zhang, Zhiyuan Niu, Taixia Wang, Xin Guan, Xiao Li, Weiwei Ren, Dou Du, Huixiong Xu, Wenwen Yue, Liping Sun   +16 more
wiley   +1 more source

Facing a Real Threat of Death: Dynamic Changes in Death-Thought Accessibility

Psychology Research and Behavior Management, 2022
Jia Zhou,1,* Yi Chen,1,* Yi Xu,2,* Bin Liao,3 Wenguang Fu4 1School of Humanities and Management Science, Southwest Medical University, Luzhou, SiChuan, 646000, People’s Republic of China; 2Department of Psychiatry, the First Affiliated ...
Zhou J, Chen Y, Xu Y, Liao B, Fu W
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Reminders of Mortality Alter Pain-Evoked Potentials in a Chinese Sample

Frontiers in Psychology, 2018
Pain is of evolutionary importance to human survival. However, the perception of pain could be changed when death-related thoughts are accessible. Although the influence of mortality salience (MS) on pain processing has been investigated in Westerners ...
Chenbo Wang, Chenbo Wang, Jing Tian
doaj   +1 more source

Unconscious Rationalization, or: How (Not) to Think about Awfulness and Death [PDF]

Many contemporary epistemologists take rational inference to be a conscious action performed by the thinker (Boghossian 2014; 2018; Valaris 2014; Malmgren 2018).
Quilty-Dunn, Jake
core  

Liver‐Targeted Gallium‐Polyphenol Network by Disrupting the ROS/NETs/PANoptosis Axis for Precision Acute Liver Injury Therapy

Advanced Science, EarlyView.
ABSTRACT Acute liver injury (ALI), driven by diverse insults such as drug toxicity and ischemia‐reperfusion, poses a high mortality risk and lacks targeted therapies. While reactive oxygen species (ROS), neutrophil extracellular traps (NETs), and a coordinated cell death pathway PANoptosis have been implicated, their interplay as a unified pathogenic ...
Xiaopeng Cai, Jian He, Jingwen Deng, Ziwei Wang, Zhongshu Wu, Kaiyue Wang, Xiang Zheng, Zhenzhen Gao, Xi Ma, Shumei Wei, Xiangrong Hu, Yuan Ding, Weilin Wang, Min Zhou   +13 more
wiley   +1 more source

From Cell‐Free Transcriptomes to Single‐Cell Landscapes: Biomarker Discovery and Originating Cell Alteration Analysis via Graph Matrix Factorization

Advanced Science, EarlyView.
CellFreeGMF traces plasma cfRNA to likely originating cell types by integrating single‐cell atlases with graph‐regularized matrix factorization. The method decomposes cfRNA profiles into sample–cell contributions to reconstruct pseudo single‐cell expression.
Wenxiang Zhang, Wenjing Zhang, Hang Wei, Shiyan Liu, Junliang Shang, Weijie Gong, Hanwen Cheng, Xiujuan Lei, Yuhui Kou, Baoguo Jiang   +9 more
wiley   +1 more source

The Impact of Mortality Salience on Mind Wandering During Reading: A Cognitive Test of Terror Management Theory [PDF]

, 2009
The effects of mind wandering on normal reading have been explored recently in studies using self-paced reading (Schooler, Reichle, & Halpern, 2004) and eye tracking (Reichle, Reineberg, & Schooler, 2009).
Reineberg, Andrew E
core  

Linguistic Structures and Economic Outcomes [PDF]

, 2017
Linguistic structures have recently started to attract attention from economists as determinants of economic phenomena. This paper provides the first comprehensive review of this nascent literature and its achievements so far.
Aarsleff, Alesina, Alesina, Alesina, Boroditsky, Boroditsky, Bradley, Broome, Bybee, Casasanto, Casasanto, Casasanto, Casasanto, Central Intelligence Agency, Chen, Chierchia, Chiswick, Chomsky, Comrie, Corbett, Corbett, Corbett, Cyffer, Dahl, Dahl, Davis, Davis, Dawkins, Di Paolo, Dryer, Duncan, Elgin, Encyclopedia Britannica, Evans, Fausey, Fausey, Fearon, Fernandez, Fernandez, Fernandez, Fernandez, Fidrmuc, Fodor, Frank, Gay, Gentner, Givati, Gleitman, Gorodnichenko, Guiso, Gumperz, Henrich, Hicks, Hicks, Hübner, Isphording, Isphording, Isphording, Jeffrey, Kashima, Kashima, Kay, Koerner, Lazear, Levinson, Levinson, Levitt, Licht, List, Lucy, Lucy, Lucy, Lucy, Majid, Marschak, Mavisakalyan, Melitz, Milles, Nurse, Pascual-Ezama, Pinker, Prinz, Regier, Richerson, Roberts, Roberts, Santacreu-Vasut, Santacreu-Vasut, Sapir, Saul, Savage, Scholz, Simons, Slobin, Spolaore, Tabellini, Takano, Tversky, Velde, Weirich, Whorf, Winawer, Yao   +102 more
core   +1 more source

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, EarlyView.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Saliencia de la mortalidad y su influencia en motivos identitarios individuales y colectivos: un estudio experimental / Mortality salience and its influence on individual and collective identity motives: an experimental study [PDF]

Liberabit, 2016
RESUMEN: La presente investigación busca determinar el impacto de la saliencia de la mortalidad en motivos identitarios individuales y colectivos, como la autoestima, la eficacia, la pertenencia, la distintividad, la continuidad y el significado.
Sebastián Campos, Agustín Espinosa
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