Results 131 to 140 of about 42,215 (293)

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

The Unconscious Influence of Mortality Salience on Younger and Older Adults [PDF]

open access: yes, 2011
Past research has examined the many ways individuals behave in response to unconscious primes. For instance, unconsciously activating stereotypes leads people to exhibit behavior that parallels the target stereotype (e.g., Bargh, Chen, & Burrows, 1996 ...
Johnson, Ellen
core   +1 more source

Model for End‐Stage Liver Disease/Pediatric End‐Stage Liver Disease exception policy and outcomes in pediatric patients with hepatopulmonary syndrome requiring liver transplantation

open access: yesLiver Transplantation, EarlyView., 2022
Abstract Hepatopulmonary syndrome (HPS) is associated with increased waitlist mortality in liver transplantation (LT) candidates. Children with HPS are granted Model for End‐Stage Liver Disease (MELD)/Pediatric End‐Stage Liver Disease (PELD) exception points for waitlist prioritization in the United States based on criterion developed for adults.
Muhammad H. Raza   +8 more
wiley   +1 more source

Reading hominin life history in fossil bones and teeth: methods to test hypotheses regarding its evolution

open access: yesBiological Reviews, EarlyView.
ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito   +2 more
wiley   +1 more source

Intolerance for the Intolerant: Possible Moderators of the Quest Effect [PDF]

open access: yes, 2006
Once viewed as a universally-tolerant religious orientation, the quest orientation has been found to be associated with decreased acceptance toward those perceived as rigid and inflexible in their belief styles.
Bates, Bethany
core  

Long‐Term Impact of Prosthesis‐Patient Mismatch After Transcatheter Aortic Valve Replacement in Patients With Small Aortic Annuli

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Prosthesis‐patient mismatch (PPM) remains common following transcatheter aortic valve replacement (TAVR) and is associated with worse clinical outcomes. PPM is of particular concern in small aortic annuli (SAA). Aims To compare the incidence, predictors, and long‐term impact of PPM in SAA TAVR.
Itamar Loewenstein   +9 more
wiley   +1 more source

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