Results 141 to 150 of about 4,721,525 (310)

Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016 [PDF]

open access: yes, 2018
Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations.

core  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Differential mortality by lifetime earnings in Germany [PDF]

open access: yes
e estimate mortality rates by a measure of socio-economic status in a very large sample of male German pensioners aged~65 or older. Our analysis is entirely nonparametric.
Hans-Martin von Gaudecker   +1 more
core  

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Years of Life Lost due to the 2015 Gorkha earthquake in Nepal

open access: yesBMC Public Health
Background Information on Years of Life Lost (YLL) is instrumental in determining the mortality impact of disasters at the population level. YLL due to the 2015 Gorkha earthquake in Nepal, along with associated demographic disparities, has not yet been ...
Margo Tonnelier   +8 more
doaj   +1 more source

A TABLE OF ABBOTT'S CORRECTION FOR NATURAL MORTALITY

open access: yesAnnals of Applied Biology, 1952
RESP ...
openaire   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Sensitivity of life disparity with respect to changes in mortality rates [PDF]

open access: yes
This article is concerned with sensitivity analysis of life disparity with respect to changes in mortality rates. A relationship is derived that describes the effect on life disparity caused by a perturbation of the force of mortality. Recently Zhang and
Peter Wagner
core  

Life history of the Colorado potato beetle, Leptinotarsa decemlineata (Say) (Coleoptera: Chrysomelidae), on four potato varieties in Iran

open access: yesJournal of Crop Protection, 2016
: Colorado potato beetle (CPB), Leptinotarsa decemlineata (Say),is the most important insect pest of potato in Iran. If local potato varieties vary in susceptibility to the pest, host plant resistance may provide management benefits to potato growers.
Shahzad Iranipour   +2 more
doaj  

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