Results 11 to 20 of about 8,745 (179)

TMEM16A Contributes to Calcium-Activated Chloride Currents and Membrane Potential Changes in the Mouse Oocyte. [PDF]

open access: yesJ Cell Physiol
ABSTRACT Oscillations in intracellular Ca2+ [Ca2+]i are essential for mouse oocyte activation following fertilization. These [Ca2+]i oscillations also induce repetitive hyperpolarizations in the membrane potential (Em). The present study aimed to identify the channels underlying the Em hyperpolarizations.
Dalati S, Jones VJ, Day ML.
europepmc   +2 more sources

Comparison of Highly Purified HMG versus Recombinant FSH with Antagonist Protocol in Poor Responder Patients

open access: yesFertility & Reproduction, 2020
Background:Luteinizing hormone (LH) supplementation may have beneficial effect on the maturity and fertilizability of oocytes in poor ovarian reserve (POR) and may influence the progesterone level, thus increasing the pregnancy rate.
Arie A. Polim   +5 more
doaj   +1 more source

Birth of spinal muscular atrophy unaffected baby from genetically at-risk parents following a pre-implantation genetic screening: A case report

open access: yesInternational Journal of Reproductive BioMedicine, 2022
Background: Spinal muscular atrophy (SMA) is characterized by the homozygous deletion of the survival motor neuron-1 gene. Pre-implantation genetic testing for monogenic diseases through in-vitrofertilization program was developed to provide a reliable ...
Arie Adrainus Polim   +7 more
doaj   +1 more source

The Clinical Embryologist: Past, Present and Future Challenges

open access: yesFertility & Reproduction, 2023
Embryologist is an essential part of infertility care defined as a highly skilled and well-trained person who can work in teamwork to execute continuous tasks with near-zero error and pay attention to detail with excellent clinical judgment.
Arief Boediono
doaj   +1 more source

A sister of NANOG regulates genes expressed in pre-implantation human development [PDF]

open access: yesOpen Biology, 2017
The NANOG homeobox gene plays a pivotal role in self-renewal and maintenance of pluripotency in human, mouse and other vertebrate embryonic stem cells, and in pluripotent cells of the blastocyst inner cell mass.
Thomas L. Dunwell, Peter W. H. Holland
doaj   +1 more source

Mitochondrial function of human embryo: Decline in their quality with maternal aging

open access: yesReproductive Medicine and Biology, 2022
Background Female fertility declines with age, due to increased chromosomal aneuploidy and possible reduced mitochondrial function in the embryo.
Shu Hashimoto, Yoshiharu Morimoto
doaj   +1 more source

Vitrification Effects on the Transcriptome of in vivo-Derived Porcine Morulae

open access: yesFrontiers in Veterinary Science, 2021
Despite the reported promising farrowing rates after non-surgical and surgical transfers of vitrified porcine morulae and blastocysts produced in vivo (range: 70–75%), the pregnancy loss is 5–15 fold higher with vitrified than with fresh embryos.
Cristina Cuello   +7 more
doaj   +1 more source

Dynamic Changes in the Proteome of Early Bovine Embryos Developed In Vivo

open access: yesFrontiers in Cell and Developmental Biology, 2022
Early embryo development is a dynamic process involving important molecular and structural changes leading to the embryonic genome activation (EGA) and early cell lineage differentiation.
Charles Banliat   +13 more
doaj   +1 more source

Clinical Relevance of Secreted Small Noncoding RNAs in an Embryo Implantation Potential Prediction at Morula and Blastocyst Development Stages

open access: yesLife, 2021
Despite the improvements in biotechnological approaches and the selection of controlled ovarian hyperstimulation protocols, the resulting pregnancy rate from in vitro fertilization (IVF) protocols still does not exceed 30–40%.
Angelika V. Timofeeva   +7 more
doaj   +1 more source

The Open Cryotop System Is Effective for the Simultaneous Vitrification of a Large Number of Porcine Embryos at Different Developmental Stages

open access: yesFrontiers in Veterinary Science, 2022
The Superfine Open Pulled Straw (SOPS) system is the most commonly used method for vitrification of pig embryos. However, this system only allows the vitrification of four to seven embryos per straw.
Alejandro Gonzalez-Plaza   +12 more
doaj   +1 more source

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