Results 211 to 220 of about 1,000,292 (319)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

High-performance Au-MoS₂-graphene multilayer SPR biosensor with superior sensitivity and precision. [PDF]

Sci Rep
Bahmani E, Kaatuzian H, Shafagh SG.
europepmc   +1 more source

Modelovanje i simulacija karakteristika MOS tranzistora naprezanih jakim električnim poljem

, 2015
S. Aleksic
openalex   +1 more source

MOLIYAVIY HISOBOTNING XALQARO IFRS STANDARTLARIGA MOS TAHLILINI AMALGA OSHIRISH: O'ZBEKISTON TAJRIBASI (IFRS 9 VA IFRS 15 STANDARTLARINING JORIY ETILISHINING BANKLARNING FOYDA KO'RSATKICHLARIGA TA'SIRI)

Iskandar B. Jumaniyazov
openalex   +1 more source

New physics couplings from angular coefficient functions of $\overline{B}\to D^{*}\left(D\pi \right)\ell {\overline{\nu }}_{\ell }$

Physical Review
The Belle Collaboration has recently measured the complete set of angular coefficient functions for the exclusive decays B¯→D*(Dπ)ℓν¯ℓ, with ℓ=e, μ, in four bins of the parameter w=mB2+mD*2−q22mBmD*, with q the lepton pair momentum [M. T. Prim et al. (Belle Collaboration), arXiv:2310.20286].
Colangelo, Pietro, De Fazio, Fulvia, Loparco, Francesco, Losacco, Nicola   +3 more
openaire  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Association of Fall-Risk Factors and Margin of Stability While Tripping in Community-Dwelling Older Adults: Experimental Pilot Study. [PDF]

JMIR Form Res
Sczuka KS, Schneider M, Kerse N, Becker C, Klenk J.   +4 more
europepmc   +1 more source

The role of electron transport and trapping in MOS total-dose modeling

, 1999
Daniel M. Fleetwood, P.S. Winokur, L.C. Riewe, O. Flament, P. Paillet, J.L. Leray   +5 more
openalex   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source