Results 281 to 290 of about 1,000,292 (319)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Radiofrequency cascade readout of coupled spin qubits. [PDF]

Nat Electron
Chittock-Wood JF, Leon RCC, Fogarty MA, Murphy T, von Horstig FE, Patomäki SM, Oakes GA, Williams J, Johnson N, Jussot J, Kubicek S, Govoreanu B, Wise DF, Morton JJL, Gonzalez-Zalba MF.   +14 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Treating Pancreatic Ductal Adenocarcinoma: The Targeted Revolution is Here. [PDF]

Drugs
May MS, Park W, O'Reilly EM.
europepmc   +1 more source

CatalyticConversion of Ethanol over Supported MoS₂ Catalysts: EnhancingActivity Using Novel Nickel-ContainingCarbon Nanofiber Materials

Mohamed E. Osman (12798256), Evgeny A. Permyakov (18983367), Nikita A. Repev (22578232), Victor M. Kogan (12798274)   +3 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A review of the current evidence for maintenance therapy in gastric cancer. [PDF]

Front Pharmacol
Han X, Zhang Y, Fan Q, Yu J, Lv L, Li Y, Hou L.   +6 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Generation of Phd2-haplodeficient macrophages with proresolution effects for the treatment of limb ischemia. [PDF]

Front Pharmacol
Alves PT, de Moura SA, Taylor H, Fidanza A, Gil CD, Martin L, Nasare AM, Lengert AVH, Garcia BBM, Guarache GC, Pereira GJDS, Jun Koh IH, Forrester LM, Han SW.   +13 more
europepmc   +1 more source

Efficient simulation of power MOS transistors

, 2011
MV Maria Ugryumova, Wha Wil Schilders
openalex   +1 more source