Results 141 to 150 of about 943,002 (392)

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

Advanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng, Haoran Sun, Jin Cheng, Ruyi Zhao, Jianzhu Xie, Yanwei Song, Yucui Zhao, Chenwei Lin, Binjie Hu, Yanping Gong, Jun Lin, Sijia He, Yuntao Luo, Minghui Zhao, Yiwei Wang, Ming Jiao, Yuqin Yang, Jikun Li, Shujie Xia, Chuanyuan Li, Qian Huang   +20 more
wiley   +1 more source

Enhancing Georeferencing and Mosaicking Techniques over Water Surfaces with High-Resolution Unmanned Aerial Vehicle (UAV) Imagery

Remote Sensing
Aquatic ecosystems are crucial in preserving biodiversity, regulating biogeochemical cycles, and sustaining human life; however, their resilience against climate change and anthropogenic stressors remains poorly understood.
Alejandro Román, Sergio Heredia, Anna E. Windle, Antonio Tovar-Sánchez, Gabriel Navarro   +4 more
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Characterization of a Rare Mosaicism in Autosomal Translocation of t(5;21) Using Conventional Cytogenetics and FISH Methods [PDF]

, 2019
Sadaf Omori Sarabi, Javad Karimzad Hagh, Claudia Behrend, Seyed Behrooz Mohseni, Mitra Ansari Dezfouli, Seyed Khalil Rashidi, Mir Davood Omrani, Mir Davood Omrani   +7 more
openalex   +1 more source

Structural Basis of the Membrane Association by the Conserved RocS Membrane‐Targeting Sequence in Streptococcus

Advanced Science, EarlyView.
Chromosome segregation in Streptococcus pneumoniae depends on RocS, a bitopic protein whose membrane‐anchoring mechanisms were unclear. Using NMR and AFM, this study reveals that the widely conserved RocS anchor binds to membranes via a conserved kink‐helix motif which inserts into lipid nanodomains.
Ana Álvarez‐Mena, Estelle Morvan, Clara Lambert, Anagha Kallisseri Parambil, Martin Lefeuvre, Zeren Xu, Nadia El Mammeri, Florian Malard, Erick J. Dufourc, Cécile Feuillie, Christophe Grangeasse, Birgit Habenstein   +11 more
wiley   +1 more source

Virus Resistant and Susceptible Transgenic Nicotiana benthamiana Plants Expressing Coat Protein Gene of Zucchini green mottle mosaic virus for LMO Safety Assessment [PDF]

, 2004
Min-Jea Kim, Sun Hee Choi, Tae Sung Kim, Min-Hye Park, Hee-Rae Lim, Kyung-Hee Oh, Tae-San Kim, Min-Hyo Lee, Ki Hyun Ryu   +8 more
openalex   +1 more source

In Situ Liquid‐Cell Transmission Electron Microscopy Insights Into Lithium‐Ion Battery Materials Degradation: Challenges and Emerging Solutions

Advanced Science, EarlyView.
Lithium‐ion battery degradation arises from complex, localized processes during operation, limiting long‐term performance. In situ electrochemical liquid cell TEM provides unique access to these mechanisms. This review summarizes degradation phenomena revealed by liquid cell TEM, traces the evolution of the three main cell designs, compares their ...
Walid Dachraoui, Rolf Erni
wiley   +1 more source

Tectonic Structure of Alaska as Evidenced by ERTS Imagery and Ongoing Seismicity [PDF]

The author has identified the following significant results. A mosaic was constructed from selected portions of eleven LANDSAT images at a scale of 1:1,000,000. Band 7 images were utilized because of their superior haze-cutting characteristics.
Gedney, L. D.
core   +1 more source

Mosaic organization of DNA nucleotides.

Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics, 1994
Chung-Kang Peng, S. Buldyrev, S. Havlin, M. Simons, H. Stanley, A. Goldberger   +5 more
semanticscholar   +1 more source

AlF3 Mediated In‐Situ Cathode Interface Stabilization Enables High‐Rate and Long‐Life Na‐Ion Batteries at Elevated Temperature

Advanced Science, EarlyView.
Ultrathin AlF3 coating facilitates the formation of an inorganic‐dominated cathode electrolyte interphase (CEI), predominantly composed of NaF/AlF3/NaAlF4. This CEI layer effectively suppresses detrimental interfacial side reactions while simultaneously enhancing the diffusion kinetics of Na+.
Ya‐Meng Yin, Qinxia Liu, Zhiyuan Zhang, Weixiao Wang, Cunyuan Pei, Fangyu Xiong, Jinghui Chen, Qinyou An, Cai‐Hong Yang, Dong‐Sheng Li   +9 more
wiley   +1 more source