Results 211 to 220 of about 2,895,342 (271)

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

Developmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard, Lauren Clarissa Tang, Beatrix Ueberheide, Lisa A. Taneyhill   +3 more
wiley   +1 more source

A spontaneously evolving multifunctional interphase enables durable cycling in solid-state lithium metal batteries. [PDF]

Chem Sci
Lin H, Xie X, Zheng F, Liu W, He X, Xiao Z, Xu W, Ding F, Liang X, Chen B, Ming L, Lin Z, Ou X.   +12 more
europepmc   +1 more source

Goofy/123Cre lineage tracing differentiates olfactory and vomeronasal neurons from GnRH‐1 and terminal nerve neurons during neuronal migration and reveals additional olfactory placode‐derived cells in the brain

Developmental Dynamics, EarlyView.
Abstract The olfactory placode (OP) generates a broad array of chemosensory neurons in the nasal region, including olfactory sensory neurons, vomeronasal sensory neurons, neurons of the septal organ, and Grueneberg ganglion. During invagination, the OP also generates migratory neuronal populations, including gonadotropin‐releasing hormone‐1 (GnRH‐1 ...
Enrico Amato Jr., Mia V. Call, Noah M. LeFever, Mya Aviles‐Carlos, Nikki M. Dolphin, Paolo E. Forni   +5 more
wiley   +1 more source

Molecular evolution of mosaic chromosome 18 copy-number alterations from gametes to hepatoblastoma. [PDF]

JHEP Rep
Cendres E, Cornet M, Gautier Z, Pire A, Urvoy N, Morcrette G, Simaga F, Guimier A, Chardot C, Capito C, Schleiermacher G, Masliah-Planchon J, Pierron G, Taddei I, Stoppa-Lyonnet D, Zucman-Rossi J, Romana S, Aerts I, Hirsch TZ.   +18 more
europepmc   +1 more source

Differential sensitivity to SHH signaling and neural crest‐mediated Gas1 expression regulate jaw size during development and evolution

Developmental Dynamics, EarlyView.
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová, Daniel B. Chu, An Nguyen, Yeniko Ta, Jennifer L. Fish, Richard A. Schneider   +5 more
wiley   +1 more source

Variability and population structure of watermelon mosaic virus in zucchini crops in Poland. [PDF]

J Gen Virol
Budzyńska D, Minicka J, Zarzyńska-Nowak A, Szkatulska M, Taberska A, Hasiów-Jaroszewska B.   +5 more
europepmc   +1 more source

MIT/TFE family transcription factors, Mitf and Tfec, redundantly promote pigment cell differentiation and retinal epithelium pigmentation in teleosts

Developmental Dynamics, EarlyView.
Abstract Background Transcription factors of the MIT/TFE family—mitfa, mitfb, and tfec—play essential roles in specifying pigment cells derived from neural crest cells in vertebrates. In teleosts, which possess multiple pigment cell types, these factors exhibit partially redundant but largely distinct functions across different pigment lineages.
James Lister, Keisuke Sugiwaka, Tetsuaki Kimura, Rieko Tanaka, Makoto Goda, Hikaru Kobayashi, Chikako Inoue, Kawilarang W. A. Masengi, Kazunori Yamahira, Kiyoshi Naruse, Satoshi Ansai, Robert N. Kelsh, Masahiko Hibi, Hisashi Hashimoto   +13 more
wiley   +1 more source

Evidence for functional convergence between LZTS2 and DYRK1A during craniofacial development

Developmental Dynamics, EarlyView.
Abstract Background Precise control of DYRK1A dosage is essential for embryonic development, including craniofacial morphogenesis. While LZTS2 is among the most consistently identified DYRK1A‐interacting proteins, its roles in embryonic development remain incompletely understood, and its potential contribution to craniofacial development has not been ...
Nicole Cheng, Santiago Lima, Larisa Litovchick, Amanda J. G. Dickinson   +3 more
wiley   +1 more source

Necro-mosaic: a lesion-aware framework for testing programmed cell-death-associated mechanisms in tuberculosis. [PDF]

Front Immunol
Zhang Q, Chang.
europepmc   +1 more source

Associations between mycorrhizal dominance and woody species diversity shift with stand development and climate across subtropical and tropical forests in Taiwan

Ecography, EarlyView.
Mycorrhizal symbioses influence woody species diversity, but whether this association shifts with forest stand development remains underexplored. Using forest inventory data across subtropical and tropical forests in Taiwan, we found that woody species diversity was lower in ectomycorrhizal (EM)‐dominated than in arbuscular mycorrhizal (AM)‐dominated ...
Albert Vilà‐Cabrera, Julen Astigarraga, Kirsten S.W. O'Sullivan, Karina E. Clemmensen, Henna Tyyskä, Sarah Greenwood, Josep Padullés Cubino, Jan‐Chang Chen, Alistair S. Jump   +8 more
wiley   +1 more source