Results 71 to 80 of about 15,973 (268)

Non-metric digital reconstruction of Roman mosaics excavated in the city of Ravenna (Italy)

Virtual Archaeology Review, 2018
During the excavations carried out in summer 2011 in Piazza Anita Garibaldi in Ravenna, during construction of the new underground  waste  containers,  five  rooms  decorated  with  mosaic  floors  were  found,  probably  dating back to  the  early Roman
Mariapaola Monti, Giuseppe Maino
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Mosaic Technology in the Armenian Chapel Birds Mosaic, Jerusalem: Characterizing the Polychrome Hidden Sinopia

Heritage
Since the Hellenistic period, preparatory drawings known as sinopiae were employed as guidelines for mosaicists in creating mosaics. The sinopiae served as the basis for style and content, facilitating the placement of colored tesserae in the supporting ...
Yotam Asscher, Giulia Ricci, Michela Reato, Ilana Peters, Abraham Leviant, Jacques Neguer, Mark Avrahami, Gilberto Artioli   +7 more
doaj   +1 more source

Structural Basis of the Membrane Association by the Conserved RocS Membrane‐Targeting Sequence in Streptococcus

Advanced Science, EarlyView.
Chromosome segregation in Streptococcus pneumoniae depends on RocS, a bitopic protein whose membrane‐anchoring mechanisms were unclear. Using NMR and AFM, this study reveals that the widely conserved RocS anchor binds to membranes via a conserved kink‐helix motif which inserts into lipid nanodomains.
Ana Álvarez‐Mena, Estelle Morvan, Clara Lambert, Anagha Kallisseri Parambil, Martin Lefeuvre, Zeren Xu, Nadia El Mammeri, Florian Malard, Erick J. Dufourc, Cécile Feuillie, Christophe Grangeasse, Birgit Habenstein   +11 more
wiley   +1 more source

Neuronal Migration and Lamination in the Vertebrate Retina

Frontiers in Neuroscience, 2018
In the retina, like in most other brain regions, developing neurons are arranged into distinct layers giving the mature tissue its stratified appearance.
Rana Amini, Mauricio Rocha-Martins, Caren Norden   +2 more
doaj   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Sensing and Reprogramming Surface Receptor Activation With Synthetic Transcriptional Circuits

Advanced Science, EarlyView.
A synthetic receptor‐signalling induced transcription (RESIT) circuit is designed based on receptor activation mediated split protease complementation and release of membrane‐tethered synthetic transcriptional modules. The RESIT system enables probing Ca2+ entry, receptor tyrosine kinase (RTK) activities and Ras activation, and reprogramming RTK ...
Fei Liu, Mei Yuan, Li‐Juan Tang, Fenglin Wang, Xia Chu, Jian‐Hui Jiang   +5 more
wiley   +1 more source

Visualización de datos y clasificación Iconclass: un estudio de caso desde la perspectiva de las Humanidades Digitales

Caracteres: Estudios Culturales y Críticos de la Esfera Digital, 2017
The Data Visualization or Data Information is mapping to abstract graphic variables in order to build a visual representation of data. This research proposal is aimed at the field of Digital Humanities, as well as its application to the Historical ...
Beatriz Garrido Ramos
doaj  

Bioinspired Microphase‐Engineered Binders for Silicon Anodes

Advanced Science, EarlyView.
Inspired by the tough exoskeleton of Phloeodes diabolicus, a bio‐based binder featuring LRA–click chemistry and hierarchical crosslinking forms well‐defined microphase‐separated structures that enable robust silicon anodes. This system promotes the formation of a LiF–rich, ultrathin SEI (∼17 nm) with high modulus and ionic conductivity, ensuring long ...
Lirong Tang, Lan Zhao, Zhiyi Cao, Fengcai Lin, Biao Huang, Haijun Li, Lingling Qian, Yingshan Shi, Yaohang Weng, Xuan Yang, Hanyang Liu, Beili Lu, Jianhua Lv, Xinda You, Jiayu Tao, Zhenwei Wu   +15 more
wiley   +1 more source

Apotheosis of monarchy by Byzantine models. The iconogmraphic program of the mosaics from Alexander-Nevsky’s Cathedral in Warsaw

Studia Humanitatis, 2020
This article is devoted to the mosaics of the Alexander Nevsky Cathedral built in Warsaw in 1894-1912. 16 magnificent mosaic panels based on sketches by Viktor Vasnetsov, Nikolai Koshelev, Nikolai Bruni, Andrey Ryabushkin and Viktor Dumitrashko ...
Walczak Dorota, Nikolsky Evgeny Vladimirovich   +1 more
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