Results 171 to 180 of about 244,158 (323)

An African Perspective on Surrogacy and the Justification of Motherhood

, 2018
Michael Aina Akande
openalex   +2 more sources

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

"Mother in the making": Motherhood performativity of childless women in rural Pakistan. [PDF]

PLoS One
Slamat R, Bracke P, Ceuterick M.
europepmc   +1 more source

Single Motherhood in East and West Germany: What Can Explain the Differences?

, 2019
Uwe Jirjahn, Cornelia Struewing
openalex   +1 more source

NanoLoop: A Deep Learning Framework Leveraging Nanopore Sequencing for Chromatin Loop Prediction

Advanced Science, EarlyView.
Chromatin loops are central to gene regulation and 3D genome organization. Leveraging Nanopore sequencing's ability to jointly capture DNA sequence and methylation, we present NanoLoop, the first framework for genome‐wide chromatin loop prediction using Nanopore data.
Wenjie Huang, Li Tang, Matthew C. Hill, Yonghao Zhang, Jun Xie, Min Li   +5 more
wiley   +1 more source

Motherhood in adolescence: a qualitative study of the lived experience of participants in a perinatal home-visiting intervention. [PDF]

Child Adolesc Psychiatry Ment Health
Chou DT, Neto EA, Fracolli LA, Fatori D, Becker N, Caye A, Soares VN, Osorio AAC, Guimarães-Fernandes F, Polanczyk GV, Miguel EC, Martin A, Benoit L.   +12 more
europepmc   +1 more source

cuteHap: Haplotype‐Aware Structural Variant Detection in Phased Long‐Read Sequencing Data

Advanced Science, EarlyView.
cuteHap is a haplotype‐aware structural variant detection method designed for phased long‐read sequencing. By employing self‐adaptive clustering and credibility‐prioritized beam search algorithms, cuteHap generates accurate haplotype‐resolved calls and outperforms state‐of‐the‐art tools.
Shuqi Cao, Yadong Liu, Miao Cui, Runtian Gao, Weimin Guo, Guohua Wang, Yadong Wang, Tao Jiang   +7 more
wiley   +1 more source

Stress from pregnancy disclosure and its impact on teen mothers' identity in Rwanda: a qualitative study. [PDF]

BMC Pregnancy Childbirth
Uwimana E, Nshimiyimana A, Musafili A, Rutembesa E, Niyonsenga J.   +4 more
europepmc   +1 more source

Fertility postponement and age norms in Poland: is there a deadline for parenthood? [PDF]

The postponement of childbearing is occurring across Europe, but the paths of this trend differ profoundly from country to country. Especially in Central and Eastern Europe, most women have their first child at a relatively young age.
Monika A. Mynarska
core  

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

Advanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa, Amruta A, LaTonya J. Hickson, Joy Wolfram   +3 more
wiley   +1 more source