Results 181 to 190 of about 1,755,813 (344)

Lactate Metabolic Reprogramming Mediated by CircRNA–LDHA Complex Facilitates Innate Immune Evasion of Liver Cancer

Advanced Science, EarlyView.
CircSMPD4 physically combines with lactate dehydrogenase A (LDHA) and reduces its acetylation level via SIRT2‐dependent deacetylation, thereby inhibiting chaperone‐mediated autophagy‐lysosome degradation of LDHA. Upregulating LDHA leads to increasing lactate production and extracellular export, which in turn suppresses natural killer cell cytotoxicity ...
Hao Shen, Boqiang Liu, Jing He, Weijun Zhao, Weiqi Li, Lingfeng Ma, Lidan Hou, Yi Wang, Chenqi Jin, Yushun Chang, Jie Lin, Jia Zhao, Binghan Jin, Yuanshi Tian, Xiujun Cai, Liang Shi, Yifan Wang   +16 more
wiley   +1 more source

NATURAL MUTATIONS IN INBRED LINES OF MAIZE AND THEIR HETEROTIC EFFECT. II. COMPARISON OF MOTHER LINE VS. MUTANT WHEN OUTCROSSED TO UNRELATED INBREDS [PDF]

, 1956
Josef F Schuler, G. F. Sprague
openalex   +1 more source

Defect‐Rich Porous Cu with Abundant Cu(100) for Acidic CO2 Electroreduction in Membrane Electrode Assembly

Advanced Science, EarlyView.
This study introduces defect‐rich porous Cu nanosheets (pCu NS) with abundant Cu(100) facets for efficient acidic CO2RR to C2+ products. The porous structure creates a localized alkaline microenvironment that hinders HER, defects enhance *CO coverage, and the Cu(100) facet facilitates *CO hydrogenation to *COH, demonstrating the essential role of facet/
Qiang Fang, Yunzhen Jia, Xuelei Lang, Geng Li, Tao Zhao, Dazhong Zhong, Jinping Li, Qiang Zhao   +7 more
wiley   +1 more source

THE WORK OF A DEPARTMENT FOR EMPLOYING EXPECTANT MOTHERS IN A MUNITION FACTORY: (Preliminary Report.) [PDF]

, 1918
R. H. B. Adamson, H. Palmer-Jones
openalex   +1 more source

Mechanisms and Pathophysiological Significance of Insulin Resistance in Offspring With Intrauterine Growth Restriction Mediated by Hepatic GR/miR‐1224 Programming

Advanced Science, EarlyView.
This work found that early‐stage insulin sensitization but late‐stage insulin resistance in prenatal caffeine exposure (PCE)‐ induced intrauterine growth restriction (IUGR) offspring may be related to the hepatic AGEs accumulation via intrauterine GR/miR‐1224 programming by glucocorticoids.
Yongguo Dai, Xiaoling Guo, Pengxia Yu, Dingmei Zhang, Hao Kou, Hui Wang   +5 more
wiley   +1 more source

MEIOSIS IN THE POLLEN MOTHER CELLS OF OENOTHERA BIENNIS AND OENOTHERA BIENNIS SULFUREA [PDF]

, 1926
Ralph E. Cleland
openalex   +1 more source

ACE‐mediated Glycosylation Stabilizes PSAP To Promote GPR37‐dependent Macrophage‐Nucleus Pulposus Cells Crosstalk and TGFβ Signaling in Alleviating Intervertebral Disc Degeneration

Advanced Science, EarlyView.
ACE can modulate the CBL‐mediated K48 ubiquitination degradation of PSAP by altering its glycosylation levels in NP cells. As a result, NP cells secrete PSAP, which interacts with GPR37 on macrophage surfaces, facilitating their polarization toward the M2 phenotype. These M2 macrophages subsequently secrete TGFβ, which exerts feedback effects on the NP
Youfeng Guo, Feng Wang, Bijun Wang, Yu Zhou, Chao Wang, Tao Hu, Desheng Wu   +6 more
wiley   +1 more source

Dyadic Relationship and Coparenting Quality During the Transition to Parenthood for Couples With Childhood Maltreatment History. [PDF]

Fam Process
Martin LN, Renshaw KD, Curby TW, Feinberg ME.   +3 more
europepmc   +1 more source

NOTES ON SOME INTERESTING CASES AT THE NEW YORK MOTHERS' HOME MATERNITY HOSPITAL. [PDF]

, 1892
T. J. McGILLICUDDY
openalex   +1 more source

Manipulating the Hydrogen‐Associated Insulator‐Metal Transition Through Artificial Microstructure Engineering

Advanced Science, EarlyView.
Establishing an unobstructed conduit for hydrogen diffusion via the artificial design of material microstructure associated with boundary configuration and crystal orientation offers a powerful tuning knob for extensively accelerating the proton mobility and enhancing electronic phase modulations, thereby advancing the high‐speed protonic device ...
Xuanchi Zhou, Xiaohui Yao, Wentian Lu, Jinjian Guo, Jiahui Ji, Lili Lang, Guowei Zhou, Chunwei Yao, Xiaomei Qiao, Huihui Ji, Zhe Yuan, Xiaohong Xu   +11 more
wiley   +1 more source