Results 31 to 40 of about 420,339 (255)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Le numérique et les normes : des normes aux affordances
Cet article se propose de renouveler la réflexion sur les normes en montrant en quoi, sur le fond d’une distinction entre différents types de normes, l’articulation de la norme, relative à la langue, et des normes (Rastier 2008), sémantiques et ...
Marion Colas-Blaise
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Modularity in Biological Networks
Network modeling, from the ecological to the molecular scale has become an essential tool for studying the structure, dynamics and complex behavior of living systems. Graph representations of the relationships between biological components open up a wide
Sergio Antonio Alcalá-Corona +8 more
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Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
БРОНЗОВЫЕ ПЕРСТНИ С ИЗОБРАЖЕНИЯМИ НА ЩИТКАХ ИЗ МОГИЛЬНИКА «БАТЫРСКИЙ 1» В РАЙОНЕ НОВОРОССИЙСКА [PDF]
Данная статья посвящена публикации бронзовых перстей, найденных при раскопках 2023 г. могильника «Батырский 1» в окрестностях Новороссийска. Погребения совершены в каменных ящиках по обряду ингумации. Рядом с могилами располагались поминальные комплексы —
Трейстер, М.Ю. +2 more
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Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
MGATs: Motif-Based Graph Attention Networks
In recent years, graph convolutional neural networks (GCNs) have become a popular research topic due to their outstanding performance in various complex network data mining tasks.
Jinfang Sheng +3 more
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source

