Results 171 to 180 of about 3,421,417 (362)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Outdoor performance of a motion-sensitive neuron in the blowfly

, 2001
Egelhaaf M, Grewe J, Kern R, Warzecha A-K. Outdoor performance of a motion-sensitive neuron in the blowfly. Vision research. 2001;41(27):3627-3637.We studied an identified motion-sensitive neuron of the blowfly under outdoor conditions.
Egelhaaf, Martin, Grewe, Jan, Anne-Kathrin Warzecha, Egelhaaf, Martin ; https://orcid.org/, Martin Egelhaaf, Kern, Roland ; https://orcid.org/, Kern, Roland, Roland Kern, Warzecha, Anne-Kathrin, Jan Grewe   +9 more
core   +1 more source

Managing lower extremity loading in distance running by altering sagittal plane trunk leaning

Journal of Sport and Health Science
Background: Trunk lean angle is an underrepresented biomechanical variable for modulating and redistributing lower extremity joint loading and potentially reducing the risk of running-related overuse injuries.
Luca Braun, Patrick Mai, Markus Hipper, Yannick Denis, Janina Helwig, Bastian Anedda, Burkay Utku, Dominic Gehring, Steffen Willwacher   +8 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

An evolutionary strategy based motion estimation algorithm for H.264 video codecs

, 2005
In this paper, we propose a new motion estimation algorithm based on evolutionary strategy (ES) for the H.264 video codec applied to monoscopic video. The proposed technique applies in macroblock basis and performs a parallel local search for the motion ...
Adedoyin, S, Loo, KK, H.K. Arachchi, Fernando, WAC, Kodikara Arachchi, H, S. Adedoyin, W.A.C. Fernando, Kalganova, T, K.K. Loo, T. Kalganova   +9 more
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Continuous martingales and Brownian motion

, 1990
Daniel Revuz, M. Yor
semanticscholar   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Comparison of lower body joint kinematics during change of direction tasks estimated using a markerless and a markerbased method

Scientific Reports
Marker-based (MB) motion capture systems face challenges like marker loss, soft tissue artifacts, and manual processing. Markerless (ML) motion capture systems might be particularly advantageous for capturing dynamic, non-linear movements like change of ...
Janina Helwig, Jos Vanrenterghem, Bastian Anedda, Daniel Koska, Markus Hipper, Yannick Denis, Luca Braun, Veerle Segers, Albert Gollhofer, Steffen Willwacher   +9 more
doaj   +1 more source