Results 61 to 70 of about 295,698 (318)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

WiFi-Based Detection of Human Subtle Motion for Health Applications

open access: yesBioengineering, 2023
Neurodegenerative diseases such as Parkinson’s disease affect motor symptoms with abnormally increased or reduced movements. Symptoms such as tremor and hand movement disorders can be subtle and vary daily such that the actual condition of the disease ...
Hui-Hsin Chen   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Review of IoT Sensor Systems Used for Monitoring the Road Infrastructure

open access: yesSensors, 2023
An intelligent transportation system is one of the fundamental goals of the smart city concept. The Internet of Things (IoT) concept is a basic instrument to digitalize and automatize the process in the intelligent transportation system.
Kristian Micko   +2 more
doaj   +1 more source

Deep Motion Boundary Detection

open access: yesCoRR, 2018
17 pages, 5 ...
Xiaoqing Yin   +5 more
openaire   +2 more sources

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Retinomorphic Motion Detector Fabricated with Organic Infrared Semiconductors

open access: yesAdvanced Science, 2023
Organic retinomorphic sensors offer the advantage of in‐sensor processing to filter out redundant static backgrounds and are well suited for motion detection.
Shuo‐En Wu   +6 more
doaj   +1 more source

People Detection and Recognition using Gait for Automated Visual Surveillance

open access: yes, 2006
In this paper, a computer vision system for automated visual surveillance in an unconstrained outdoor environment is described. We propose a method for tracking multiple moving objects based on shape-based feature correspondence between consecutive ...
I. Bouchrika   +3 more
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

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