Results 71 to 80 of about 3,619,573 (385)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Numerically "exact" approach to open quantum dynamics: The hierarchical equations of motion (HEOM).

Journal of Chemical Physics, 2020
An open quantum system refers to a system that is further coupled to a bath system consisting of surrounding radiation fields, atoms, molecules, or proteins. The bath system is typically modeled by an infinite number of harmonic oscillators.
Y. Tanimura
semanticscholar   +1 more source

Replicating physical motion with Minkowskian isorefractive spacetime crystals

Nanophotonics, 2023
Abstract Here, we show that isorefractive spacetime crystals with a travelling-wave modulation may mimic rigorously the response of moving material systems. Unlike generic spacetime crystals, which are characterized by a bi-anisotropic coupling in the co-moving frame, isorefractive crystals exhibit an observer-independent response ...
Prudêncio Filipa R., Silveirinha Mário G.   +1 more
openaire   +4 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The Design of One-Dimensional Motion and Two-Dimensional Motion Learning Media Using Digital Camera and Tracker-Based Air Track

JPPPF: Jurnal Penelitian & Pengembangan Pendidikan Fisika, 2020
This research describes the results of the development of 2D air track tools designed for one and two-dimensional motion experiments with small frictional forces.
Fransisca Indra Dewi, Nur Aji Wibowo, Debora Natalia Sudjito, Ferdy Rondonuwu   +3 more
doaj   +1 more source

Development of Force and Motion Concept Self-Efficacy Inventory (FMCSEI) for Senior High School Students

Jurnal Penelitian dan Pembelajaran IPA, 2023
This study aimed to develop and validate the Force and Motion Concept Self-Efficacy Inventory (FMCSEI), a content-specific self-efficacy inventory for the senior high school level.
Albert Andry E. Panergayo
doaj   +1 more source

Influence of internal structure on the motion of test bodies in extreme mass ratio situations

, 2012
We investigate the motion of test bodies with internal structure in General Relativity. With the help of a multipolar approximation method for extended test bodies we derive the equations of motion up to the quadrupolar order.
Puetzfeld, Dirk, Steinhoff, Jan
core   +1 more source

Spatial Structure and Coherent Motion in Dense Planetary Rings Induced by Self-Gravitational Instability [PDF]

, 1999
We investigate the formation of spatial structure in dense, self-gravitating particle systems such as Saturn's B-ring through local $N$-body simulations to clarify the intrinsic physics based on individual particle motion.
A G W Cameron, A P Hatzes, A Toomre, B A Smith, D C Richardson, D N C Lin, D Sugimoto, E Griv, F G Bridges, G W Hill, H Salo, H Salo, H Salo, H Salo, J Binney, J Lukkari, J Makino, J Makino, J P Dilley, J Wisdom, K D Supulver, K Nakazawa, K Ohtsuki, K Ohtsuki, K Ohtsuki, L Dones, L W Esposito, L W Esposito, L W Esposito, P Goldreich, P Goldreich, P Goldreich, S Araki, S Araki, S Araki, S Ida, S Ida, S Ida, W H Julian, W H Press, W K Hartmann, W R Ward   +41 more
core   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Analysis of Students' Understanding of Concepts in Straight Motion Material in Physics Learning

International Journal of Education and Teaching Zone, 2023
The research was conducted in order to be able to analyze understanding of concepts in straight motion material. The research that was carried out used a quantitative research type with a descriptive approach to the population of 20 students in physics ...
Fera Maya Fitriyani, Siti Rohmah, Boby Yasman Purnaman, Bahman Zohuri   +3 more
doaj   +1 more source