Results 51 to 60 of about 148,549 (266)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

A Novel Human Motion Tracking Approach Based on a Wireless Sensor Network

International Journal of Distributed Sensor Networks, 2013
This paper proposes a human motion tracking approach for a daily life surveillance in a distributed wireless sensor network using ultrasonic range sensors.
Sen Zhang, Wendong Xiao, Jun Gong, Yixin Yin   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Fast and Simple Motion Tracking Unit with Motion Estimation

Journal of Measurement Science and Instrumentation, 2010
Surveillance system using active tracking camera has no distance limitation of surveillance range compared to supersonic or sound sensors.However,complex motion tracking algorithm requires huge amount of computation,and it often requires expensive DSPs ...
Hyeon-cheol YANG1, Yoon-sup KIM1, Seong-soo LEE1, Sang-keun OH2, Sung-hwa KIM2, Doo-won CHOI2   +5 more
doaj  

A flexible motion tracking system based on inertial sensors

MATEC Web of Conferences, 2018
As a newly emerging human-computer interaction, motion tracking technology offers a way to extract human motion data. This paper presents a series of techniques to improve the flexibility of the motion tracking system based on the inertial measurement ...
Han Zhonghao, Hu Lei, Guo Na, Yang Biao, Liu Hongsheng, Wang Yuhan   +5 more
doaj   +1 more source

Motion analysis by feature tracking

Vision Research, 1998
We have developed a two-stage model of motion perception that identifies moving spatial features and computes their velocity, achieving both high spatial localisation and reliable estimates of velocity. Features are detected in each frame by locating the peaks of the spatial local energy functions, as for stationary images (Morrone MC and Burr DC. Proc
Del Viva MM, MORRONE, MARIA CONCETTA
openaire   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source