Results 191 to 200 of about 582,776 (293)

RiemannInfer: improving transformer inference through Riemannian geometry. [PDF]

Sci Rep
Mao R, Zhang Z, Yang M, Xie H, Wei S, Hu C.   +5 more
europepmc   +1 more source

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

Advanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv, Yu Cao, Yuhan Wang, Yunhao Wu, Yingying Zhang, Kuanghao Ye, Xian Qiu, Qingfang Sun, Liuguan Bian, Halimureti Paerhati, Valerie Voon, Shikun Zhan, Bomin Sun   +12 more
wiley   +1 more source

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

Advanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty, Kamal el Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs. Szigyártó, Loránd Románszki, Natália Tőkési, Daniel Pinkas, Eszter Házy, Olivér Pavela, Andrea Bodor, Zoltán Varga, István Mándity, Mihály Kovács, Csaba Pál, Kata Horváti, Judit Tóth, Tamás Beke‐Somfai   +21 more
wiley   +1 more source

HOIMamba: Bidirectional State-Space Modeling for Monocular 3D Human-Object Interaction Reconstruction. [PDF]

Biomimetics (Basel)
Zhang J, Lin Y.
europepmc   +1 more source

Understanding Fabrication Variability in Core‐Shell Soft Biomaterials Using Stochastic Artificial Intelligence

Advanced Science, EarlyView.
Fabrication‐induced variability remains a fundamental limitation in the scalable design of soft biomaterials. In this work, a stochastic machine learning approach based on Gaussian processes modeling is employed to establish quantitative links between biofabrication parameters, material properties, and their intrinsic variability.
Maria Alexaki, Lília M. S. Dias, Raquel C. Gonçalves, Dinis O. Abranches, Albano N. Carneiro Neto, Rute A. S. Ferreira, Paulo S. B. André, João F. Mano, Mariana B. Oliveira   +8 more
wiley   +1 more source

"Irresponsible Not to Share Such Important Information": A Narrative of Responsibility That Underpins Familial Disclosure of Genetic Risk in Singapore. [PDF]

Bioethics
Ong S.
europepmc   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

LLM-DWA: a hybrid path planning framework combining large language models with the dynamic window approach. [PDF]

Sci Rep
Seo J, Kim E, Choi AJ.
europepmc   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

The Dark Side of Moral Conviction-Integrating Political Psychology, Cognitive Science, and Neuroscience. [PDF]

Ann N Y Acad Sci
Decety J, Cohen MS, Cao Q.
europepmc   +1 more source