Results 231 to 240 of about 2,396,578 (330)

The Future of Workplaces: Monitoring Health and Safety Conditions Using Wearable Technologies.

Indian J Occup Environ Med
Ramesh N, Joseph B.
europepmc   +1 more source

The Relationship Between Emotional Intelligence and the Risk of Eating Disorders Among Adolescents: The Mediating Role of Motivation for the Use of Social Media and Moderation of Perceived Social Support. [PDF]

Behav Sci (Basel)
Riolo M, Piombo MA, Spicuzza V, Novara C, La Grutta S, Epifanio MS.   +5 more
europepmc   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

The hidden risk of round numbers and sharp thresholds in clinical practice. [PDF]

NPJ Digit Med
Lengerich BJ, Caruana R, Nunnally ME, Kellis M.   +3 more
europepmc   +1 more source

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

Advanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen   +18 more
wiley   +1 more source

Epidemiological and Clinical Profile of Fixed Pigmented Erythema at the Departmental University Hospital Center Borgou/Alibori (Benin). [PDF]

Dermatol Res Pract
Akpadjan F, Dotsop L, Agbessi N, Koudoukpo C.   +3 more
europepmc   +1 more source

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source

An Update to the Middle-Range Theory of Self-Care of Chronic Illness. [PDF]

ANS Adv Nurs Sci
Riegel B, Riegel B, Jaarsma T, Strömberg A.   +3 more
europepmc   +1 more source

‘Grandma’s Hands’: Valuing Students’ Identities and Motivated Signs

Changing English
openaire   +1 more source

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

Advanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang, Yuli Zhang, Zixin Kang, Jiayun Xiong, Ronghua Yang, Kang Ning   +5 more
wiley   +1 more source