Results 241 to 250 of about 2,396,578 (330)

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Tramadol use among young commercial drivers in Tamale Metropolis: a concurrent triangulation mixed-methods study. [PDF]

Subst Abuse Treat Prev Policy
Awugah PA, Tanko A, Daliri DB, Adjei D, Abagye N.   +4 more
europepmc   +1 more source

Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors

Advanced Science, EarlyView.
Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl, Finn Jaekel, Julia Henne, Richard Kantelberg, Daniel C. Freund, Eberhard Grambow, Brigitte Vollmar, Amelie R. Zitzmann, Hans Kleemann, Jochen Hampe, Sebastian Hinz, Clemens Schafmayer, Karl Leo   +12 more
wiley   +1 more source

Gastric torsion associated with a type IV hiatal hernia in two cats. [PDF]

JFMS Open Rep
Deschildre F, Blondel M, Soliveres E, Chanoit G.   +3 more
europepmc   +1 more source

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source

PathCare: Integrating Clinical Pathway Information to Enable Healthcare Prediction at the Neuron Level. [PDF]

Bioengineering (Basel)
Sui D, Gu L, Zhang C, Yang K, Li X, Ma L, Wang L, Tang W.   +7 more
europepmc   +1 more source

Body Art: A Study on Aesthetics and Postural Instability in Patients With Piercings. [PDF]

Cureus
Caricato F, Noto AM, Sanzone E, Donati P, Parchi PD.   +4 more
europepmc   +1 more source

Non-Contrast CT Hemorrhage Markers and Outcomes in Intracerebral Hemorrhage: A Large Single-Center Cohort from Romania. [PDF]

Reports (MDPI)
Cindea C, Saceleanu V, Canning P, Roman-Filip C, Mihaila R.   +4 more
europepmc   +1 more source