Results 51 to 60 of about 1,473,664 (393)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

The Effect of Individual Learning Programs on Self-Efficacy and Learning Motivation of Students With Special Needs at Inclusive Schools

open access: yesSekolah Dasar: Kajian Teori dan Praktik Pendidikan, 2023
The study's objectives were as follows: 1) to identify the difference between self-efficacy of students with special needs before (pretest) and after (post-test) being taught with the PPI; 2) to determine the difference in learning motivation of students
Dwhy Dinda Sari
doaj   +1 more source

Effects of Using a Blended Learning Method on Students’ Achievement and Motivation to Learn English in Jordan: A Pilot Case Study

open access: yesEducation Research International, 2018
This research aims at investigating the effect of blended learning on the achievement and motivation to learn English of German Jordanian University students. A pilot case study research strategy was used.
Thelal Oweis
semanticscholar   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Self Concepts and Motivation To Learn Among Students [PDF]

open access: yes, 2004
Abtract: In Malaysia, more than half of the population are adolescent and most of them are students who are still studiying either in schools or in higher institutions of learning.
Yahaya, Azizi
core  

Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers

open access: yesFEBS Open Bio, EarlyView.
Microbial biosynthesis and engineered enzyme platforms are expanding the design space of polyhydroxyalkanoate bioplastics. By combining fermentation, PHA synthase engineering and cell‐free modular systems, tailored biodegradable polymers can be produced with tunable properties, supporting more sustainable materials and future circular bioeconomy ...
Giovanni Gallo   +4 more
wiley   +1 more source

Motivating Weak Students: A Critical Discussion and Reflection [PDF]

open access: yes, 2012
The motivation of students is regarded as one of the problems in the higher education. One of the reasons for the increasing number of students with low-level of motivation is that there are many students join universities without adequate level of ...
Ganah, Abdulkadir
core  

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

A SURVEY ON MOTIVATIONAL ORIENTATION IN LEARNING EFL OF PUBLIC ADMINISTRATION POST GRADUATE STUDENTS OF JENDERAL SOEDIRMAN UNIVERSITY [PDF]

open access: yes, 2013
This study investigated instrumental and integrative motivations (motivational orientation) of a group of EFL students, namely post graduate students of Public Administration in Jenderal Soedirman University.
Rochman, Syaifur
core  

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