Results 201 to 210 of about 141,166 (265)

Modeling information demand in the framework of probabilistic reasoning. [PDF]

Commun Psychol
Jiwa MW, Gottlieb J.
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

From guesstimates to game changers: Introducing objective measurement of blood loss for timely postpartum hemorrhage detection in Nigeria, Zambia, and Kenya. [PDF]

Int J Gynaecol Obstet
Njogu R, Tappis H, Orji BC, Kapoma S, Adepoju VA, Ndhlovu M, Roman E, Muthamia MM, Lathrop E, Evans C.   +9 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Why Adolescents Choose to Stop or Never Start Vaping: Evidence From South Africa. [PDF]

Nicotine Tob Res
van den Bosch A, Filby S, Florence M, van Zyl-Smit RN, Kurten S.   +4 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Legal Infoveillance of Unlicensed Medical Practices in South Korea Through Criminal Court Decisions Using Machine Learning: Retrospective Observational Study. [PDF]

JMIR Public Health Surveill
Kim MJ, Choi M.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Clinical care processes for early postpartum haemorrhage diagnosis: a nested observational study within the E-MOTIVE trial. [PDF]

Front Glob Womens Health
Mammoliti KM, Althabe F, Easter C, Martin J, Devall AJ, Funmi AL, Yusuf R, Abubakar F, Arigbede LC, Mugambi J, Oyoo P, Sambusa M, Banda A, Samuels F, Willemse S, Khambule SD, Shu'aib HM, Wakili AA, Okore J, Mwampashi A, Singata-Madliki M, Arends E, Muller E, Galadanci H, Qureshi Z, Al-Beity FA, Fawcus S, Moran N, Gwako G, Osoti A, Gallos I, Coomarasamy A.   +31 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source