Results 51 to 60 of about 11,769 (219)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Personal trainer - occupational choices determinants

open access: yesJournal of Education, Health and Sport, 2017
Fitness service market is currently dynamically growing in Poland. As a result fitness services portfolio is rapidly broadening and clients interest in that matter escalates as well, therefore personal trainers profession seemed to be a great ...
Aleksandra Leśniewska
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Increase of competitiveness of the personnel: Internal control and stimulation

open access: yesПутеводитель предпринимателя, 2020
In work it is investigated and the assumption is put forward that one of tools of management of competitiveness of the personnel of workers is formation and development of system of internal control of the commercial organization, taking into account its

doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

STUDY REGARDING VISIBILITY OF ALBA COUNTY MAIN TOURISTIC OBJECTIVES [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
The present study investigates the familiarity of main touristic destinations that are present in Alba County from the tourist’s point of view. In order to respond to the purpose of the paper the authors formulated a series of objectives.
DÂRJA MĂLINA , LAZEA RUXANDRA
doaj  

EMOTIONAL FACTOR OF STUDENT LEARNING: CONTENT, STRUCTURE AND SIGNIFICANCE IN SECURITY QUALITIES OF EDUCATION

open access: yesОсвітній вимір, 2009
The article deals with the problem of the emotional factor of instruction structure and essence. Author defines the notion emotional factor of instruction establishes the significance of emotional factors at the guaranteeing quality of the modern ...
Yu.O. Saunova
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Literary face of Lovran

open access: yesZbornik Lovranšćine, 2010
This work outlines the thesis about permanent literal production of Lovran and from Lovran. Considering this goal different literary works are presented and analyzed, in chronological manner, texts and notes considered in wider, cultural understanding of
Vjekoslava Jurdana
doaj  

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