Results 281 to 290 of about 1,194,513 (315)

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

open access: yesAging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

The Long Term Effects of a 12‐Session Community Exercise Program on Health Measures in Cancer Patients

open access: yesAging and Cancer, EarlyView.
ABSTRACT Purpose To assess the long‐term effects of a community cancer exercise program on quality of life, fatigue, weight, waist circumference, physical activity levels, lower extremity strength, body mass index (BMI), heart rate, and blood pressure, across non‐metastatic and metastatic patients.
Isaac Oppong, Roozbeh Naemi
wiley   +1 more source

A review of artificial intelligence in brachytherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen   +4 more
wiley   +1 more source

Toward a human‐centric co‐design methodology for AI detection of differences between planned and delivered dose in radiotherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Introduction Many artificial intelligence (AI) solutions have been proposed to enhance the radiotherapy (RT) workflow, but limited applications have been implemented to date, suggesting an implementation gap. One contributing factor to this gap is a misalignment between AI systems and their users.
Luca M. Heising   +11 more
wiley   +1 more source

Position‐dependent offset corrections for ring applicator reconstruction in cervical cancer brachytherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Due to the tight curvature in their design, ring applicators are usually associated with large positioning errors. The standard practice to correct for these deviations based on global offsets may not be sufficient to comply with the recommended tolerance.
Leon G. Aldrovandi   +3 more
wiley   +1 more source

Design and validation of a novel dosimetry phantom for motion management audits

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background We present a novel phantom design for conducting end‐to‐end dosimetry audits for respiratory motion management of two anatomical treatment sites. The design enables radiochromic film measurements of the dose administered to the target throughout the respiratory cycle (motion‐included) and the dose delivered to the time‐averaged ...
Alex Burton   +5 more
wiley   +1 more source

A Python package for fast GPU‐based proton pencil beam dose calculation

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Open‐source GPU‐based Monte Carlo (MC) proton dose calculation algorithms provide high speed and unparalleled accuracy but can be complex to integrate with new applications and remain slower than GPU‐based pencil beam (PB) methods, which sacrifice some physical accuracy for sub‐second plan calculation.
Mahasweta Bhattacharya   +4 more
wiley   +1 more source

The Motor Activity Anxiety Test [PDF]

open access: possiblePerceptual and Motor Skills, 1994
Feelings and perceptions of insecurity, anxiety, and danger can hinder motor learning and performance. The Motor Activity Anxiety Test is proposed to assess personal attitude to meet typical motor requirements for physical education in schools and anxiety about the physical dangers linked to motor activities in particular.
BORTOLI, Laura, ROBAZZA, Claudio
openaire   +3 more sources

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