Results 41 to 50 of about 589,719 (314)

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

How Can Promoting Skeletal Muscle Health and Exercise in Children and Adolescents Prevent Insulin Resistance and Type 2 Diabetes?

open access: yesLife
Skeletal muscle secretome, through its paracrine and endocrine functions, contributes to the maintenance and regulation of overall physiological health.
Valeria Calcaterra   +7 more
doaj   +1 more source

Assessing the effectiveness of learning a complex motor activity in children aged 9-10 years

open access: yesJournal of Education, Health and Sport, 2022
Introduction Learning is a complex and multi-dimensional process that depends on cognitive and emotional processes and the development of functional systems of the human body. One type of learning is motor learning.
Dawid Matczak, Marta Wieczorek
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Center of Pressure Feedback Modulates the Entrainment of Voluntary Sway to the Motion of a Visual Target

open access: yesApplied Sciences, 2019
Visually guided weight shifting is widely employed in balance rehabilitation, but the underlying visuo-motor integration process leading to balance improvement is still unclear. In this study, we investigated the role of center of pressure (CoP) feedback
Haralampos Sotirakis   +4 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Analysis of motor activity of premature newborns [PDF]

open access: yesĶazaķstannyṇ Klinikalyķ Medicinasy, 2017
Objective: The article studies the clinical features of the motor system of premature newborns, a possible prognosis for development has been determined and the program of non-drug rehabilitation of children born with a burdened perinatal anamnesis ...
Tamara Chuvakova   +2 more
doaj   +1 more source

Intermittent rectal motor activity: a rectal motor complex? [PDF]

open access: yesGut, 1991
Prolonged nocturnal recordings from multiple sites in the anorectum and duodenum were performed in 12 healthy volunteers to investigate the presence and determine the characteristics of nocturnal rectal motor activity and assess any synchronicity with phase III of the small intestinal migrating motor complex.
U J Fearn, A Prior, N W Read
openaire   +3 more sources

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

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