Results 191 to 200 of about 264,565 (302)

Summer Success: SKIPing to Motor Competence for Disadvantaged Preschoolers. [PDF]

Children (Basel)
Brandon D, Famelia R, Webster EK, Goodway JD.   +3 more
europepmc   +1 more source

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

Advanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng, Jia‐Jia Liang, Yun‐Feng Zhan, Wei‐Xun Wu, Wan‐Li Xu, Xiao‐Kun Zhang, Li‐Jun Cai, Fu‐Quan Jiang   +7 more
wiley   +1 more source

Adherence to different types of sports shapes motor competence development in preschool children. [PDF]

Sci Rep
Guo X, Li C, Zhao J, Yang W, Xu Q, Kawczyński A, Clemente FM.   +6 more
europepmc   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

A Quasi-Experimental Hip-Hop-Based Program to Improve Motor Competence and Physical Activity in Preschoolers in Portugal: The "Grow+" Program. [PDF]

Healthcare (Basel)
Mercê C, Bernardino S, Saramago N, Branco M, Catela D.   +4 more
europepmc   +1 more source

⁠Engineering Adaptive Immunity in 3D: A Patient‐Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells

Advanced Science, EarlyView.
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley   +1 more source

Developmental Changes in Motor Competence: The Influence of Physical Activity and BMI Percentile. [PDF]

Med Sci Sports Exerc
Wood AP, Palmer KK, Ouyang Z, Wang L, Robinson LE, Robinson LE.   +5 more
europepmc   +1 more source

Motor Learning and Motor Development as a Motor Competence Problem Throughout Lifespan [PDF]

Research & Investigations in Sports Medicine, 2018
openaire   +1 more source

MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Advanced Science, EarlyView.
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li   +10 more
wiley   +1 more source

Sports participation and sex outweigh the relative age effect in motor competence of school-aged children. [PDF]

Front Sports Act Living
Flôres F, Soares D, Silva AF, Casanova N, Almeida G, Marmeleira J, Shabanliyski D.   +6 more
europepmc   +1 more source