Results 141 to 150 of about 289,368 (258)

Somatic gene mutations in the motor cortex of patients with sporadic amyotrophic lateral sclerosis. [PDF]

Brain
González-Velasco Ó, Parlato R, Yilmaz R, Decker L, Menge S, Freischmidt A, Yang X, Tulasi N, Brenner D, Andersen PM, Forsberg KME, Schlachetzki JCM, Brors B, Voith von Voithenberg L, Weishaupt JH.   +14 more
europepmc   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Nanoplatforms for Sentinel and Tumor‐Draining Lymph Node Mapping: From Visualization to Pathway‐Informed Staging

Advanced Healthcare Materials, EarlyView.
Lymphotropic nanoplatforms integrate multimodal imaging with therapeutic guidance to map sentinel and tumor‐draining lymph nodes, revealing functional drainage, metastatic involvement, and nodal accessibility, while providing mechanistic insight to support precision surgical and therapeutic interventions.
Xu Chen, Nina Li, Meiyan Zou, Zihao Zhou, Rongwei Xu, Weiyao Feng, Xinyuan Zhao, Li Cui   +7 more
wiley   +1 more source

Handgrip weakness is associated with motor cortex atrophy in rheumatoid arthritis: a cross-sectional study with a hand exercise intervention. [PDF]

BMC Med
Gustafsson AL, Heckemann RA, Erlandsson MC, Lundgren VM, Dai Z, Silfverswärd ST, Pullerits R, Bokarewa MI, Wasén C.   +8 more
europepmc   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Synaptosomes isolated from cryopreserved MND motor cortex reveal altered calcium handling and reduced complex IV-linked respiration. [PDF]

Front Synaptic Neurosci
Morrison SD, Ragnarsson L, Cook SO, Rothnagel JA, Wolvetang E, Al-Mhanawi B, Shaker MR, Robertson T, Dodd PR, Noakes PG.   +9 more
europepmc   +1 more source

The curse of dimensionality in motor cortex.

bioRxiv : the preprint server for biology
Understanding how motor cortex generates movement is a foundational challenge in neuroscience [50]. Unsupervised dimensionality reduction techniques, such as principal component analysis (PCA), are widely used to transform high-dimensional neural data into a more interpretable, low-dimensional space [12].
Silvernagel, Michael P, Tor, Alice Y, Jun, Elizabeth J, Clarke, Stephen E, Sutherland, Robert, Marshall, Kenji, Wu, Yuxin, Abdulla, Muhammad, Even-Chen, Nir, Nuyujukian, Paul   +9 more
openaire   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

The frequency-dependent effects of primary hand motor cortex stimulation on volitional finger movement. [PDF]

Clin Neurophysiol Pract
Taquet L, Conway BJ, Boerger TF, Goetschel K, Young SC, Botros NE, Raghavan M, Schmit BD, Krucoff MO.   +8 more
europepmc   +1 more source

Neuromorphic Electronics for Intelligence Everywhere: Emerging Devices, Flexible Platforms, and Scalable System Architectures

Advanced Materials, EarlyView.
The perspective presents an integrated view of neuromorphic technologies, from device physics to real‐time applicability, while highlighting the necessity of full‐stack co‐optimization. By outlining practical hardware‐level strategies to exploit device behavior and mitigate non‐idealities, it shows pathways for building efficient, scalable, and ...
Kapil Bhardwaj, Roshni Satheesh Babu, Yuxin Xia, Eva Bestelink, Radu Sporea, Nikos Hastas, Ioannis Zeimpekis, Dimitra G. Georgiadou, Sayani Majumdar   +8 more
wiley   +1 more source