Results 191 to 200 of about 2,267,071 (351)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Cluttering in Children and Adolescents: Speech Motor Development, Neurocognitive Mechanisms, and Allied Health Implications. [PDF]

Children (Basel)
Han W, Zhou L, Lu J, Pill S.
europepmc   +1 more source

Sex differences in prenatal oral-motor function and development [PDF]

, 2007
J L Miller, Christian Macedonia, BC Sonies   +2 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Motor development in toddlers prenatally exposed to maternal cancer treatment: a national cohort study in the Netherlands. [PDF]

EClinicalMedicine
Kruse AM, Huis In 't Veld EA, van Grotel M, Amant F, van Tinteren H, van den Heuvel-Eibrink MM, Verwaaijen EJ.   +6 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Physical Activity and Sex as Predictors of Motor Development in Serbian Preschoolers. [PDF]

Sports (Basel)
Đurović M, Stupar D, Petković E, Lilić A, Pelemiš V, Mijalković S, Stamenković S.   +6 more
europepmc   +1 more source

Impact of the pellets on the physical development and motor efficiency 12-year olds

, 2013
Krzysztof Żołnowski, Krzysztof Prusik, Katarzyna Prusik, Walery Żukow   +3 more
openalex   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The Influence of Pregnancy Risk Factors on Patterns of Sensory Processing Disorders and Motor Development. [PDF]

J Clin Med
Szczepara-Fabian M, Emich-Widera E, Kazek B, Paprocka J.   +3 more
europepmc   +1 more source