Results 121 to 130 of about 147,703 (303)

Early Failure Detection and Diagnostics of High Speed Self Aligning Journal Bearing [PDF]

Because of their high load carrying capacity and low cost, journal bearings are widely used to support the rotor of industrial machinery with high loads, such as steam turbines, centrifugal compressors and pumps.
Al Thobiani, Faisal, Ball, Andrew, Gu, Fengshou, Raharjo, Parno   +3 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Learning to Hear Broken Motors: Signature-Guided Data Augmentation for Induction Motor Diagnostics

The application of machine learning (ML) algorithms in the intelligent diagnosis of three-phase engines has the potential to significantly enhance diagnostic performance and accuracy. Traditional methods largely rely on signature analysis, which, despite being a standard practice, can benefit from the integration of advanced ML techniques. In our study,
Ali, Saraa, Khizhik, Aleksandr, Svirin, Stepan, Ryzhikov, Artem, Derkach, Denis   +4 more
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Nonlinear recurrence analysis of piezo sensor placement for unmanned aerial vehicle motor failure diagnosis

Scientific Reports
This paper is focused on the diagnostics of multicopter UAV propulsion system, in which the temporary transient states occur during operation in faulty conditions (eg. not all motor phases working properly).
Andrzej Koszewnik, Leszek Ambroziak, Daniel Ołdziej, Paweł Dzienis, Bartłomiej Ambrożkiewicz, Arkadiusz Syta, Ghada Bouattour, Olfa Kanoun   +7 more
doaj   +1 more source

Equipment concept design and development plans for microgravity science and applications research on space station: Combustion tunnel, laser diagnostic system, advanced modular furnace, integrated electronics laboratory [PDF]

Taking advantage of the microgravity environment of space NASA has initiated the preliminary design of a permanently manned space station that will support technological advances in process science and stimulate the development of new and improved ...
Fiske, M. R., Georgekutty, T., Uhran, M. L., Wear, W. O., Youngblood, W. W.   +4 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Clinical value of motor function of digestive system investigation: past, present and future

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2013
The aim of review. To demonstrate modern methods of investigation of motor function of the esophagus, stomach, small and large intestine, anorectal area and their clinical value.Key points.
A. S. Trukhmanov, O. A. Storonova, V. T. Ivashkin   +2 more
doaj  

Hybrid Modeling of an Induction Machine to Support Bearing Diagnostics

IEEE Open Journal of the Industrial Electronics Society
In this article, a novel hybrid model of an induction machine is proposed that can emulate the response of a machine with a faulty bearing. The idea behind developing such a topology is to have the response quite close to that from a real asset while ...
Praneet Amitabh, Dimitar Bozalakov, Frederik De Belie   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source