Results 121 to 130 of about 2,377,140 (335)

Prevalence of cell phone use while driving in different urban settings. A roadside observational study in maputo city, Mozambique

open access: yesHeliyon
Introduction: All forms of cell phone use while driving poses a threat to traffic safety. Few studies have reported the prevalence from low- and middle-income countries where the risk of severe road traffic crashes is highest.
Alfredo Júlio Maposse   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Towards an Operational Definition of Lean Construction Onsite [PDF]

open access: yes, 2015
Through literature review and drawing from a combined professional experience of over 20 years of lean construction implementation, this paper investigates the key success factor for the automotive industry’s uptake of lean production to see what the ...
Koskela, Lauri   +2 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Multimodal driver emotion recognition using motor activity and facial expressions

open access: yesFrontiers in Artificial Intelligence
Driving performance can be significantly impacted when a person experiences intense emotions behind the wheel. Research shows that emotions such as anger, sadness, agitation, and joy can increase the risk of traffic accidents.
Carlos H. Espino-Salinas   +6 more
doaj   +1 more source

Design and manufacturing of a Selective Laser Sintering test bench to test sintering materials [PDF]

open access: yes, 2016
The goal of this project is to design and build a prototype of recoating system for a laser cutting machine to turn it into a selective laser sintering printing machine.
Gall Trabal, Guillem   +1 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Colour Vision Deficiency: Prevalence and Associated Socio-demographic Characteristics among Commercial Motor-Vehicle Drivers in Benin City Metropolis, Edo State, Nigeria

open access: yesBabcock University Medical Journal
Objectives: Colour vision deficiency (CVD) is a suggested risk factor in road traffic injuries and deaths globally. This study aimed to determine the prevalence of CVD and associated socio-demographic characteristics (SDCs) among commercial motor ...
John Moyegbone   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy