Results 141 to 150 of about 391,763 (361)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Active nutation controller [PDF]
An apparatus is described for controlling nutation motion in a spinning body, comprised of an angular accelerometer with its input axis perpendicular to the spin axis of the body, a flywheel with an axis of rotation perpendicular to the axis of the ...
Donohue, J. H., Hoffman, H. C.
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A review on model predictive control strategies for AC motor drives
In the past decade, model predictive control (MPC) has been widely used in AC motor drives. Although a series of improved MPC strategies have been proposed, researchers are still seeking more effective solutions for different application backgrounds and ...
Chen Li, Qinghui Meng, Tingna Shi
doaj +1 more source
Switched Reluctance Motors and Drive Systems for Electric Vehicle Powertrains: State of the Art Analysis and Future Trends [PDF]
Yuanfeng Lan +6 more
openalex +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
As electric forklifts advance, the electric machine‐pump/motor control system is key to their lifting system due to high efficiency. Traditional systems struggle with quadrant switching in permanent magnet synchronous machines and pump coupling, causing ...
Qihuai Chen +5 more
doaj +1 more source
Joint Synthesis of Controller and Fault Detector and Its Application to Motor Drive Control System
Hisahide Nakamura +4 more
openalex +2 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

