Results 51 to 60 of about 129,554 (354)
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Motor and Somatosensory Evoked Potential Monitoring Without Wakeup Test during Scoliosis Surgery
Journal of Rawalpindi Medical College, 2019 Background: Available evidence suggests that Transcranial electric motor evoked potentials and somatosensory evoked potential are safe methods to check the integrity of the spinal cord during spine deformity correction surgery. We compare the efficacy of
Muhammad Kamran Ayoob +5 more
doaj
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Journal of Pain Research, 2022 Hongli Yue,1,* Man Zhou,2,* Yingzi Chong,1 Miao Cheng,1 Hui Qiao,3 Yu Lu,1 Weihua Cui1 1Department of Anesthesiology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Anesthesiology ...
Yue H +6 more
doaj
Statistical Model of Motor-Evoked Potentials
IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2019 Motor-evoked potentials (MEPs) are widely used for biomarkers and dose individualization in transcranial stimulation. The large variability of MEPs requires sophisticated methods of analysis to extract information fast and correctly. Development and testing of such methods relies on the availability for realistic models of MEP generation, which are ...
Stefan M. Goetz +3 more
openaire +3 more sources
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
Acta Veterinaria Scandinavica, 2017 Somatosensory evoked potentials (SSEPs) and motor evoked potentials (MEPs) are non-invasive neurophysiological tests that reflect the functional integrity of sensory and motor pathways.
Maria Claudia Campos Mello Inglez de Souza +3 more
doaj +1 more source
Brain Stimulation, 2023 Neurophysiological effects of transcranial direct current stimulation (tDCS) have been extensively studied over the primary motor cortex (M1). Much less is however known about its effects over non-motor areas, such as the prefrontal cortex (PFC), which ...
Mohsen Mosayebi-Samani +5 more
doaj +1 more source
BDNF val66met polymorphism is associated with modified experience-dependent plasticity in human motor cortex. [PDF]
, 2006 Motor training can induce profound physiological plasticity within primary motor cortex, including changes in corticospinal output and motor map topography.
Chan, Sheila +6 more
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