Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik+4 more
wiley +1 more source
Preliminary Effects of Extended Reality-Based Rehabilitation on Gross Motor Function, Balance, and Psychosocial Health in Children with Cerebral Palsy. [PDF]
Lim O, Kim Y, Park C.
europepmc +1 more source
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun+5 more
wiley +1 more source
Early nanoparticle intervention preserves motor function following cervical spinal cord injury. [PDF]
Hocevar SE+7 more
europepmc +1 more source
Battery of behavioral tests in mice that models age-associated changes in human motor function
J. Justice+6 more
semanticscholar +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts+8 more
wiley +1 more source
Association of free-water imaging data for the cholinergic nucleus with the motor function and subtypes in Parkinson's disease. [PDF]
Xu S+6 more
europepmc +1 more source
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira+14 more
wiley +1 more source
Estimation of Stroke's Motor Function Ability Using Multimodal Biomarkers and the Role of Contralesional Motor Area. [PDF]
Kim DH, Kwon GH, Lee SW, Kim L.
europepmc +1 more source