Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The Neural Basis of Age-Related Changes in Motor Imagery of Gait: An fMRI Study [PDF]
Background. Aging is often associated with modifications of gait. Recent studies have revealed a strong relationship between gait and executive functions in healthy and pathological aging.
Allali, Gilles +5 more
core
A large body of evidence shows that motor imagery and action execution behaviors result from overlapping neural substrates, even in the absence of overt movement during motor imagery.
Magda Mustile +5 more
doaj +1 more source
Body-specific motor imagery of hand actions: neural evidence from right- and left-handers
If motor imagery uses neural structures involved in action execution, then the neural correlates of imagining an action should differ between individuals who tend to execute the action differently.
Roel M Willems +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Task-dependent activation of distinct fast and slow(er) motor pathways during motor imagery [PDF]
Background: Motor imagery and actual movements share overlapping activation of brain areas but little is known about task-specific activation of distinct motor pathways during mental simulation of movements.
Aridan +25 more
core +1 more source
User’s Self-Prediction of Performance in Motor Imagery Brain–Computer Interface
Performance variation is a critical issue in motor imagery brain–computer interface (MI-BCI), and various neurophysiological, psychological, and anatomical correlates have been reported in the literature.
Minkyu Ahn +3 more
doaj +1 more source
Feature Extraction of Motor Imagery EEG via Discrete Wavelet Transform and Generalized Maximum Fuzzy Membership Difference Entropy: A Comparative Study [PDF]
Yinan Wang +5 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

