Results 101 to 110 of about 43,477 (290)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Abnormalities of Motor Imagery and Relationship With Depressive Symptoms in Mildly Disabling Relapsing-Remitting Multiple Sclerosis [PDF]

The effectiveness of motor imagery (MI) as an adjunct to physical rehabilitation has previously been shown. Motor imagery ability can be affected by neurologic disorders that affect motor and cognitive function.
Mazhari, Shahrzad, Moghadas Tabrizi, Yousef, Nazari, Mohammad Ali, Sheibani, Vahid, Zangiabadi, Nasser   +4 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Multi-Class Classification Methods for EEG Signals of Lower-Limb Rehabilitation Movements

Biomimetics
Brain–Computer Interfaces (BCIs) enable direct communication between the brain and external devices by decoding motor intentions from EEG signals.
Shuangling Ma, Zijie Situ, Xiaobo Peng, Zhangyang Li, Ying Huang   +4 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The Motor Imagery (MI) Intervention and Rubber Ball Grafting Therapy on Rehabilitation and Increasing Motor Strength in Stroke Patients: Literature Review

Journal of Applied Nursing and Health
Background: Strokes are A disease caused narrowing of the vessels blood to the brain, which can obstruct Genre blood and also oxygen to the brain, and also can stop. Objective from the literature review This is For now influence motor imagery (MI) intervention and therapy holding a rubber ball to rehabilitation and improvement strength motor skills in ...
Chilyatiz Zahroh, Yurike Septianingrum, Eva Vera Zulkarnain   +2 more
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A mixed methods exploration of motor imagery in autistic and non-autistic adults: Diverse experiences and implications for interventions.

PLoS ONE
Research on motor imagery (MI) in non-autistic individuals suggests that there are shared neural circuitries between imagery and execution. The relationship between imagined and executed movements, and the use of MI in autistic adults is poorly ...
Molly Brillinger, Ying Bai, April Karlinsky, Timothy N Welsh, Ellen Poliakoff, Emma Gowen   +5 more
doaj   +1 more source

Visual and kinesthetic modes affect motor imagery classification in untrained subjects

Scientific Reports, 2019
The understanding of neurophysiological mechanisms responsible for motor imagery (MI) is essential for the development of brain-computer interfaces (BCI) and bioprosthetics.
Parth Chholak, Guiomar Niso, Vladimir A. Maksimenko, Semen A. Kurkin, Nikita S. Frolov, Elena N. Pitsik, Alexander E. Hramov, Alexander N. Pisarchik   +7 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source