Results 191 to 200 of about 130,421 (296)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Motor cortical mapping of proximal upper extremity muscles following spinal cord injury [PDF]

, 1997
Brenda Brouwer, Diana Hopkins‐Rosseel
openalex   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Mapping of the Rat's Motor Area after Hemispherectomy: The Hemispheres as Potentially Independent Motor Brains [PDF]

, 2003
André G. Machado, Alexandre Shoji, Gerson Ballester, Raul Marino   +3 more
openalex   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Hereditary motor and sensory neuropathy – Lom (HMSNL): refined genetic mapping in Romani (Gypsy) families from several European countries

, 2000
David Chandler, Dora Angelicheva, Lisa Heather, Rebecca Gooding, David Gresham, Peter Yanakiev, Roos de Jonge, Frank Baas, Danielle E. Dye, Luchezar Karagyozov, Alexei Savov, Karin Blechschmidt, Bronya J.B. Keats, P K Thomas, R. H. M. King, Arnold Starr, Amelia Nikolova, J. Colomer, Boryana Ishpekova, Ivailo Tournev, Jon Andoni Urtizberea, Luciano Merlini, Duśan Butinar, B. Chabrol, Thomas Voit, Martina Baethmann, V. Nedkova, Axinia Corches, Luba Kalaydjieva   +28 more
openalex   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

AB-195. EloQ. Application for mapping of the non-motor eloquent cortex during awake surgery

М. В. Синкин, Anastasia A. Skalnaya, Alexey Voskoboynikov, Magomed Aliverdiev, Alexey Ossadtch   +4 more
openalex   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Brain-to-brain hyperclassification reveals action-specific motor mapping of observed actions in humans. [PDF]

PLoS One, 2017
Smirnov D, Lachat F, Peltola T, Lahnakoski JM, Koistinen OP, Glerean E, Vehtari A, Hari R, Sams M, Nummenmaa L.   +9 more
europepmc   +1 more source