Results 231 to 240 of about 130,421 (296)

Emerging paradigms in connectome-guided neurosurgery for central nervous system tumors: a narrative review of structural and functional connectomics. [PDF]

Ann Med Surg (Lond)
Patel T, Yousuf Ibrahim H, Abbas M, Amir Ali M, Sohrab S, Nawaz K, Zehra SF, Patel BD, Anand N.   +8 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Limb apraxia and active inference in the visuomotor pathways. [PDF]

Psychon Bull Rev
Proietti R, Pezzulo G, Binkofski F, Tessari A.   +3 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Non-Invasive Measurement of Cortical Plasticity in Brain Tumour Surgery: A Monocentric Experience of nTMS Mapping and Definition of Cognitive Reshaping Based on Tumour Histological Grade. [PDF]

Cancers (Basel)
Bonaudo C, Schapira ME, Pieropan E, Caredda C, Van Reeth E, Fedi F, Castaldi E, Baldanzi F, Troiano S, Maiorelli A, Pedone A, Visocchi E, Montcel B, Carrai R, Grippo A, Campagnaro L, Tola S, Della Puppa A.   +17 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The Neuromuscular Junction Distribution in the Upper Face: An Anatomy-to-Practice Review to Inform Botulinum Toxin Type A Treatment Planning. [PDF]

J Cosmet Dermatol
Magacho-Vieira FN.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

What Can Neurosurgical Pediatric Populations Do in Functional Magnetic Resonance Imaging? Brain Activity Mapping Before Intervention Tasks, a Retrospective Study. [PDF]

Brain Sci
Guarracino I, Maieron M, D'Agostini S, Skrap M, Cogo P, Ius T, Tomasino B.   +6 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source