Results 101 to 110 of about 285,147 (300)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Editorial: From depth (needle) to surface: electromyography as a diagnostic tool in identifying neuromuscular changes associated with neurological disorders

Frontiers in Human Neuroscience, 2023
Rajat Emanuel Singh, Kamran Iqbal, Jongsang Son   +2 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

LabVIEW FPGA Implementation Of a PID Controller For D.C. Motor Speed Control [PDF]

Iraqi Journal for Electrical and Electronic Engineering, 2010
This Paper presents a novel hardware design methodology of digital control systems. For this, instead of synthesizing the control system using Very high speed integration circuit Hardware Description Language (VHDL), LabVIEW FPGA module from National
Fakhrulddin H. Ali , Mohammed Mahmood Hussein , Sinan M.B. Ismael   +2 more
doaj  

Identifikasi Sistem Motor DC dan Kendali Linear Quadratic Regulator Berbasis Arduino-Simulink Matlab

Majalah Ilmiah Teknologi Elektro, 2018
This paper describes the identification process of DC motor system with experimental technique using indetification tool in Matlab. After the DC motor model system is obtained, the optimal control technique in this case using linear quadratic regulator ...
Fahmizal Fahmizal, Fahmy Fathuddin, Rudi Susanto   +2 more
doaj   +1 more source

Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex. [PDF]

Nat Commun, 2023
Jia J, Hilal T, Bohnsack KE, Chernev A, Tsao N, Bethmann J, Arumugam A, Parmely L, Holton N, Loll B, Mosammaparast N, Bohnsack MT, Urlaub H, Wahl MC.   +13 more
europepmc   +1 more source

Propulsion Wheel Motor for an Electric Vehicle [PDF]

A wheel assembly for an electric vehicle includes a wheel rim that is concentrically disposed about a central axis. A propulsion-braking module is disposed within an interior region of the wheel rim.
Bluethmann, William J., Eggleston, IV, Raymond Edward, Farrell, Logan Christopher, Figuered, Joshua M., Guo, Raymond, Herrera, Eduardo, Junkin, Lucien Q., Lee, Chunhao J., Rogers, James Jonathan, Vitale, Robert L., Waligora, Thomas M., Weber, Steven J., Winn, Ross Briant   +12 more
core   +1 more source

Constraining the Size Growth of the Task Space with Socially Guided Intrinsic Motivation using Demonstrations [PDF]

, 2011
This paper presents an algorithm for learning a highly redundant inverse model in continuous and non-preset environments. Our Socially Guided Intrinsic Motivation by Demonstrations (SGIM-D) algorithm combines the advantages of both social learning and ...
Baranes, Adrien, Nguyen, Sao Mai, Oudeyer, Pierre-Yves   +2 more
core   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Complex Burn Region Module (CBRM) update [PDF]

Presented here is a Complex Burn Region Module (CBRM) update for the Solid Rocket Internal Ballistics Module (SRIBM) Program for the Advanced Solid Rocket Motor (ASRM) design/performance assessments.
Adams, Carl L., Jenkins, Billy
core   +1 more source