Results 341 to 350 of about 2,351,931 (407)

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

The FindMNDBiomarker Program: Protein Changes in Motor Neuron Disease/Amyotrophic Lateral Sclerosis Postmortem Tissue and Biofluids. [PDF]

Ann Neurol
Adler GL, Kiernan MC, Tan RH.
europepmc   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Activated Microglia Mediate the Motor Neuron-, Synaptic Denervation- and Muscle Wasting-Changes in Burn Injured Mice. [PDF]

J Cachexia Sarcopenia Muscle
Chen J, Kitagawa Y, Xie F, Li H, Kem WR, You Z, Yasuhara S, Martyn JAJ.   +7 more
europepmc   +1 more source

Plasma troponin T reflects lower motor neuron involvement on electromyography in amyotrophic lateral sclerosis. [PDF]

Brain Commun
Chamoun S, Imrell S, Upate Z, Kläppe U, Öijerstedt L, Yazdani S, Andersson Franko M, Foucher J, Azizi L, Lovik A, Samuelsson K, Press R, Fang F, Svennberg E, Juto A, Ingre C.   +15 more
europepmc   +1 more source

Differential motor neuron activity in rats during successful and failed grasping. [PDF]

Cereb Cortex
Viaro R, Bernardi D, Maggiolini E, D'Ausilio A, Ferroni CG, Parmiani P, Fadiga L.   +6 more
europepmc   +1 more source

Sertm2 is a conserved micropeptide that promotes GDNF-mediated motor neuron subtype specification. [PDF]

EMBO Rep
Hsu FY, Yen YP, Fan HC, Chang M, Chen JA.   +4 more
europepmc   +1 more source

In vitro analog of operant conditioning in aplysia. II. Modifications of the functional dynamics of an identified neuron contribute to motor pattern selection.

, 1999
Romuald Nargeot, Douglas A. Baxter, John H. Byrne   +2 more
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