Results 141 to 150 of about 1,099,877 (344)
The motor theory of social cognition: a critique [PDF]
, 2004 Pierre Jacob, Marc Jeannerod
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Structural Reliability Analysis Based on IPSO-SVR for High-speed EMU Motor Hanger
机车电传动, 2020 Aiming at the problem that the limit state equation of high-speed EMU motor hanger is difficult to be expressed by precise mathematical analytic formula and the heavy workload of traditional reliability calculation method, the reliability analysis of ...
Yonghua LI, Yue XU, Fuyu ZHAO, Yue WU
doaj
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Traffic fatalities and economic growth [PDF]
The authors examine the impact of income growth on the death rate due to traffic fatalities, as well as on fatalities per motor vehicle and on the motorization rate (vehicles/population) using panel data from 1963-99 for 88 countries.
Cropper, Maureen, Kopits, Elizabeth
core
Green’s function method in the theory of Brownian motors
, 2018 В. М. Розенбаум +2 more
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Searching, Stepping, and Stomping: What Polymer Theory can teach us about the Molecular Motor Myosin V [PDF]
, 2013 Michael Hinczewski +2 more
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source